Biologically active protein gradients via microstamping

被引:18
作者
Bhangale, SM [1 ]
Tjong, V [1 ]
Wu, L [1 ]
Yakovlev, N [1 ]
Moran, PM [1 ]
机构
[1] Inst Mat Res & Engn, Singapore 117602, Singapore
关键词
D O I
10.1002/adma.200400547
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Protein gradients on substrates are prepared using a microstamping technique. An Au pattern is transferred from a patterned silicon stamp to a polymeric substrate, and exposed polymer regions are then selectively activated for protein immobilization. The protein gradient is achieved by varying the spacing between the exposed polymer regions (see Figure).
引用
收藏
页码:809 / +
页数:6
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