Histological evaluation of effectiveness of platelet-rich fibrin on healing of sinus membrane perforations: A preclinical animal study

被引：16

作者：

Aricioglu, Ceyhun ^{[1
]}

Dolanmaz, Dogan ^{[2
]}

Esen, Alparslan ^{[3
]}

Isik, Kubilay ^{[3
]}

Avunduk, Mustafa Cihat ^{[4
]}

机构：

[1] Konya Oral & Dent Hlth Hosp, Parsana Mh Beyhekim Cd 3, TR-42070 Selcuklu, Konya, Turkey

[2] Selcuk Univ, Dept Oral & Maxillofacial Surg, Fac Dent, TR-42250 Selcuklu, Konya, Turkey

[3] Necmettin Erbakan Univ, Dept Oral & Maxillofacial Surg, Fac Dent, Ankara Cd 74, TR-42050 Karatay, Konya, Turkey

[4] Necmettin Erbakan Univ, Dept Med Pathol, Fac Med, Yunus Emre Mh, TR-42080 Meram, Konya, Turkey

来源：

JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY | 2017年 / 45卷 / 08期

关键词：

Platelet-rich fibrin; Sinus floor augmentation; Rabbits; Collagen; Fibroblasts; Lymphocytes; SOLE GRAFTING MATERIAL; MAXILLARY SINUS; FLOOR ELEVATION; SCHNEIDERIAN MEMBRANE; IMPLANT PLACEMENT; LIFT PROCEDURES; BIO-OSS; BONE; AUGMENTATION; METRONIDAZOLE;

D O I：

10.1016/j.jcms.2017.05.005

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

The aim of this study was to evaluate the effectiveness of platelet-rich fibrin (PRF) in repairing of Schneiderian membrane perforations in rabbit maxillary sinus. A total of 42 female New Zealand rabbits were randomly divided into two groups. Symmetrical bony defects were created 1 cm in diameter and the sinus membranes were exposed. The Schneiderian membranes were elevated in both sinuses and each membrane was perforated with a 1 cm incision. No treatment was applied to the right perforations in both groups. Left-sided perforations were closed with collagen membrane in the first group and PRF membrane in the other group. Seven animals randomly selected from each group were sacrificed at weeks 1, 2 and 4 in order to be able to examine the amounts of lymphocytes, fibroblasts, veins, and collagen fibers in the area where the membranes were applied. Histological analyses showed that there were no statistically significant differences between the collagen membrane and the PRF membrane in the healing of sinus perforation area. PRF may be considered as an alternative application to collagen membrane in sinus membrane perforations. (C) 2017 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

引用

页码：1150 / 1157

页数：8

共 40 条

[1]

Aimetti M, 2001, INT J PERIODONT REST, V21, P581

[2] The clinical significance of sinus membrane perforation during augmentation of the maxillary sinus [J].

Ardekian, L ;

Oved-Peleg, E ;

Mactei, EE ;

Peled, M .

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2006, 64 (02) :277-282

[3] Prospective observation of 41 perforations of the Schneiderian membrane during sinus floor elevation [J].

Becker, Stephan Thomas ;

Terheyden, Hendrik ;

Steinriede, Anja ;

Behrens, Eleonore ;

Springer, Ingo ;

Wiltfang, Joerg .

CLINICAL ORAL IMPLANTS RESEARCH, 2008, 19 (12) :1285-1289

[4]

Biglioli F, 2010, Minerva Stomatol, V59, P299

[5] Effect of platelet-rich plasma with autogenous bone graft for maxillary sinus augmentation in a rabbit model [J].

Butterfield, KJ ;

Bennett, Y ;

Gronowicz, G ;

Adams, D .

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2005, 63 (03) :370-376

[6] Methods to Treat the Edentulous Posterior Maxilla: Implants With Sinus Grafting [J].

Chiapasco, Matteo ;

Zaniboni, Marco .

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2009, 67 (04) :867-871

[7] The use of autologous fibrin glue for closing sinus membrane perforations during sinus lifts [J].

Choi, BH ;

Zhu, SJ ;

Jung, JH ;

Lee, SH ;

Huh, JY .

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY, 2006, 101 (02) :152-156

[8] Platelet-rich fibrin (PRF): A second-generation platelet concentrate. Part V: Histologic evaluations of PRF effects on bone allograft maturation in sinus lift [J].

Choukroun, J ;

Diss, A ;

Simonpieri, A ;

Girard, MO ;

Schoeffler, C ;

Dohan, SL ;

Dohan, AJJ ;

Mouhyi, J ;

Dohan, DM .

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY, 2006, 101 (03) :299-303

[9]

Dohan David M, 2006, Oral Surg Oral Med Oral Pathol Oral Radiol Endod, V101, pe45, DOI 10.1016/j.tripleo.2005.07.009

[10] Three-Dimensional Architecture and Cell Composition of a Choukroun's Platelet-Rich Fibrin Clot and Membrane [J].

Ehrenfest, David M. Dohan ;

Del Corso, Marco ;

Diss, Antoine ;

Mouhyi, Jaafar ;

Charrier, Jean-Baptiste .

JOURNAL OF PERIODONTOLOGY, 2010, 81 (04) :546-555

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