Microrheology of entangled F-actin solutions

被引：265
作者：
Gardel, ML [1 ]
Valentine, MT
Crocker, JC
Bausch, AR
Weitz, DA
机构：
[1] Harvard Univ, Dept Phys, Cambridge, MA 02138 USA
[2] Harvard Univ, DEAS, Cambridge, MA 02138 USA
[3] Univ Penn, Dept Chem & Biomol Engn, Philadelphia, PA 19104 USA
[4] Tech Univ Munich, Lehrstuhl Biophys E22, D-8046 Garching, Germany
来源：
PHYSICAL REVIEW LETTERS | 2003年 / 91卷 / 15期
关键词：
D O I：
10.1103/PhysRevLett.91.158302
中图分类号：
O4 [物理学];
学科分类号：
0702 ;
摘要：
We measure the viscoelasticity of entangled F-actin over length scales between 1 and 100 mum using one- and two-particle microrheology, and directly identify two distinct microscopic contributions to the elasticity. Filament entanglements lead to a frequency-independent elastic modulus over an extended frequency range of 0.01-30 rad/sec; this is probed with one-particle microrheology. Longitudinal fluctuations of the filaments increase the elastic modulus between 0.1 and 30 rad/sec at length scales up to the filament persistence length; this is probed by two-particle microrheology.
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页数：4
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