Organic Synthesis: March of the Machines

被引：378

作者：

Ley, Steven V. ^{[1
]}

Fitzpatrick, Daniel E. ^{[1
]}

Ingham, Richard. J. ^{[1
]}

Myers, Rebecca M. ^{[1
]}

机构：

[1] Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2015年 / 54卷 / 11期

基金：

英国工程与自然科学研究理事会;

关键词：

analytical tools; automated optimization; control systems; organic methodology; sustainable chemistry; CONTINUOUS-FLOW PROCESS; SUPERCRITICAL CARBON-DIOXIDE; ONLINE IR ANALYSIS; CHEMICAL-REACTIONS; CHEMISTRY; OPTIMIZATION; MICROREACTORS; SYSTEM; CAMERA; SPECTROSCOPY;

D O I：

10.1002/anie.201410744

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Organic synthesis is changing; in a world where budgets are constrained and the environmental impacts of practice are scrutinized, it is increasingly recognized that the efficient use of human resource is just as important as material use. New technologies and machines have found use as methods for transforming the way we work, addressing these issues encountered in research laboratories by enabling chemists to adopt a more holistic systems approach in their work. Modern developments in this area promote a multi-disciplinary approach and work is more efficient as a result. This Review focuses on the concepts, procedures and methods that have far-reaching implications in the chemistry world. Technologies have been grouped as topics of opportunity and their recent applications in innovative research laboratories are described.

引用

页码：3449 / 3464

页数：16

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