Mass spectrometry in proteomics

被引：961

作者：

Aebersold, R ^{[1
]}

Goodlett, DR ^{[1
]}

机构：

[1] Inst Syst Biol, Seattle, WA 98105 USA

来源：

CHEMICAL REVIEWS | 2001年 / 101卷 / 02期

关键词：

D O I：

10.1021/cr990076h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Current methods that are the basis for proteome analysis are reviewed. Focus is on mass spectrometric strategies for protein identification from biological matrixes, computational approaches for searching sequence databases, determination of protein expression levels, and characterization of phosphoproteins and phosphopeptides.

引用

页码：269 / 295

页数：27

共 267 条

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