Ebola virus: from discovery to vaccine

被引：232

作者：

Feldmann, H ^{[1
]}

Jones, S

Klenk, HD

Schnittler, HJ

机构：

[1] Univ Manitoba, Natl Microbiol Lab, Special Pathogens Program, Winnipeg, MB, Canada

[2] Univ Manitoba, Dept Med Microbiol, Winnipeg, MB, Canada

[3] Univ Manitoba, Dept Immunol, Winnipeg, MB, Canada

[4] Univ Marburg, Inst Virol, D-35032 Marburg, Germany

[5] Tech Univ Dresden, Med Fac Carl Gustav Carus, Inst Physiol, Dresden, Germany

来源：

NATURE REVIEWS IMMUNOLOGY | 2003年 / 3卷 / 08期

基金：

加拿大健康研究院;

关键词：

D O I：

10.1038/nri1154

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Ebola virus, being highly pathogenic for humans and non-human primates and the subject of former weapons programmes, is now one of the most feared pathogens worldwide. In addition, the lack of pre- and post-exposure interventions makes the development of rapid diagnostics, new antiviral agents and protective vaccines a priority for many nations. Further insight into the ecology, immunology and pathogenesis of Ebola virus will promote the delivery of these urgently required tools.

引用

页码：677 / 685

页数：9

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