Laboratory tests of particle removal were performed with a pair of carbon fiber ionizers installed upstream of a glass fiber air filter. For air flow face velocities of 0.4, 0.6, and 0.8 m/s, the overall particle removal efficiencies of the filter for all submicron particles were 17%, 16%, and 14%, respectively, when the ionizers were not turned on. These values increased to 27%, 23%, and 19%, respectively, when the ionizers were used to generate ions of 6.0 x 10(9) ions/cm(3) in concentration. The carbon fiber ionizers were then installed in front of a glass fiber air filter located in a heating, ventilation, and air-conditioning (HVAC) system. Field tests were performed in a test office room with a total indoor particle concentration of 2.2 x 10(4) particles/cm(3). When the flow rate was 75 cubic meters per hour (CMH), the steady-state values of the total indoor particle concentrations using the glass fiber air filter with and without ionizers decreased to 0.87 x 10(4) particles/cm(3) and 1.15 x 10(4) particles/cm(3), respectively, resulting in a 25% decrease of the ionizer effect. When the operation flow rate was increased to 115 and 150 CMH, the effect of the ionizer decreased to 19% and 17%, respectively. These experimental data match the results calculated using a mass-balance model whose parameters were determined from laboratory tests. (C) 2011 Elsevier Ltd. All rights reserved.