The instability of electrostatic ion cyclotron wave in a plasma consisting of isotropic hydrogen ions (H+), oxygen ions (both positively and negatively charged and denoted by O+ and O-) and electron. ESIC waves with multi component plasma have been studied by kinetic approach at different plasma densities. The dispersion relation and growth rate of the electrostatic ion-cyclotron waves with multi-ion plasma has been investigated. The effect of different plasma densities on ESIC waves in multi-ions is to enhance the growth rate of ESIC waves. The results are interpreted for the space plasma parameters appropriate to the auroral acceleration region of earth's magneto-plasma.