Functionalisation of heteroaromatic N-oxides using organic superbase catalyst

被引：42

作者：

Araki, Yuta ^{[1
]}

Kobayashi, Koji ^{[1
]}

Yonemoto, Misato ^{[1
]}

Kondo, Yoshinori ^{[1
]}

机构：

[1] Tohoku Univ, Grad Sch Pharmaceut Sci, Aoba Ku, Sendai, Miyagi 9808578, Japan

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2011年 / 9卷 / 01期

关键词：

BASE-INDUCED DEPROTONATION; GRIGNARD-REAGENTS; INTRAMOLECULAR CYCLIZATION; 1-ACYLPYRIDINIUM SALTS; ELECTROPHILIC REACTION; CONVENIENT METHOD; LEAVING GROUP; T-BU-P4; BASE; PYRIDINE; ACTIVATION;

D O I：

10.1039/c0ob00740d

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Functionalisation of quinoline N-oxide was investigated using phophazene base as a catalyst; alkynylation and heteroarylation at 2-position were successfully achieved via nucleophilic addition-elimination process.

引用

页码：78 / 80

页数：3

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