Study on Proline-Catalyzed Facile Synthesis of Novel 3-(α,β-Unsaturated carbonyl)-4-hydroxy-quinolin-2(1H)-ones and Their Fluorescent Properties

被引：0

作者：

Ye, Jiahai ^{[1
]}

Wu, Jun ^{[2
]}

Huang, Nianfeng ^{[1
]}

Zhang, Wenchao ^{[1
]}

Yu, Shuyan ^{[2
]}

Qin, Zhichun ^{[1
]}

Wang, Zhiyong ^{[1
]}

Shang, Yongjia ^{[2
]}

机构：

[1] Nanjing Univ Sci & Technol, Sch Chem Engn, Nanjing 210094, Peoples R China

[2] Anhui Normal Univ, Coll Chem & Mat Sci, Anhui Key Lab Funct Mol Solids, Wuhu 241000, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2010年 / 30卷 / 10期

关键词：

proline; aldol reaction; 4-hydroxy-quinolin-2-one; fluorescence; HIV-1; REVERSE-TRANSCRIPTASE; DRUG-RESISTANCE PROPERTIES; NONNUCLEOSIDE INHIBITORS; ALDOL CONDENSATION; DERIVATIVES; DESIGN; ACID; ANTIOXIDANT; ALKALOIDS;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The aldol reaction of 3-acetyl-4-hydroxy-2(1H)-ones with aromatic aldehydes catalyzed by L-proline was carried out to give novel 3-(alpha,beta-unsaturated carbonyl)-4-hydroxy-2(1H)-ones which were separated from the solvent as pure compounds efficiently. The yields of products were affected by the properties of substitutes in aromatic aldehydes. This result confirmed a new reaction mechanism. The study on the fluorescent properties of some products revealed that this class of compounds is potential fluorescent probes.

引用

页码：1548 / 1554

页数：7

共 31 条

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