Therapeutic approaches to non-Hodgkin's lymphoma in the elderly patient

被引：1

作者：

Ninan, Mary J. ^{[3
]}

Morrison, Vicki A. ^{[1
,2
]}

机构：

[1] Vet Affairs Med Ctr, Hematol Oncol Sect, Minneapolis, MN 55417 USA

[2] Vet Affairs Med Ctr, Infect Dis Sect, Minneapolis, MN USA

[3] Univ Minnesota, Div Hematol Oncol & Transplantat, Minneapolis, MN 55455 USA

来源：

EXPERT REVIEW OF HEMATOLOGY | 2009年 / 2卷 / 02期

关键词：

diffuse large-cell lymphoma; elderly; follicular lymphoma; NHL; non-Hodgkin's lymphoma; R-CHOP; rituximab; B-CELL LYMPHOMA; DETUDE-DES-LYMPHOMES; PHASE-II TRIAL; ANTI-CD20; MONOCLONAL-ANTIBODY; CHEMOTHERAPY PLUS RITUXIMAB; RANDOMIZED CONTROLLED-TRIAL; TERM-FOLLOW-UP; LOW-GRADE; CHOP CHEMOTHERAPY; IBRITUMOMAB TIUXETAN;

D O I：

10.1586/EHM.09.7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The incidence of non-Hodgkin's lymphoma (NHL) is increasing among all age groups, with a median age at diagnosis of 67 years. With the increase in the geriatric population, there is a need for the development and validation of treatment strategies for NHL for these patients. Therapy in elderly patients is affected by multiple factors, especially comorbidities. Over the past decade, some treatment trials have included older patients. The disease incidence, characteristics and treatment approaches for both follicular and diffuse aggressive NHL histologies in elderly patients are reviewed, as well as the impact of aging on the care of these patients.

引用

页码：173 / 182

页数：10

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