Migraine and its psychiatric comorbidities

被引:356
作者
Minen, Mia Tova [1 ]
De Dhaem, Olivia Begasse [2 ]
Van Diest, Ashley Kroon [3 ]
Powers, Scott [4 ]
Schwedt, Todd J. [5 ]
Lipton, Richard [6 ]
Silbersweig, David [7 ]
机构
[1] NYU, Langone Med Ctr, Dept Neurol, 240 East 38th St,20th Floor, New York, NY 10016 USA
[2] NYU, Langone Med Ctr, Dept Internal Med, New York, NY 10016 USA
[3] Cincinnati Childrens Med Ctr, Div Behav Med & Clin Psychol, Cincinnati, OH USA
[4] Cincinnati Childrens Med Ctr, Headache Ctr, Off Clin & Translat Res, Ctr Child Behav & Nutr Res & Training Pediat, Cincinnati, OH USA
[5] Mayo Clin, Dept Neurol, Phoenix, AZ USA
[6] Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USA
[7] Brigham & Womens Hosp, Dept Psychiat, 75 Francis St, Boston, MA 02115 USA
关键词
POSTTRAUMATIC-STRESS-DISORDER; QUALITY-OF-LIFE; GENERALIZED ANXIETY DISORDER; C-REACTIVE PROTEIN; RESTING-STATE; EPISODIC MIGRAINE; BIPOLAR DISORDER; FUNCTIONAL CONNECTIVITY; STANDARDS SUBCOMMITTEE; PERCEIVED STRESS;
D O I
10.1136/jnnp-2015-312233
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Migraine is a highly prevalent and disabling neurological disorder associated with a wide range of psychiatric comorbidities. In this manuscript, we provide an overview of the link between migraine and several comorbid psychiatric disorders, including depression, anxiety and post-traumatic stress disorder. We present data on psychiatric risk factors for migraine chronification. We discuss the evidence, theories and methods, such as brain functional imaging, to explain the pathophysiological links between migraine and psychiatric disorders. Finally, we provide an overview of the treatment considerations for treating migraine with psychiatric comorbidities. In conclusion, a review of the literature demonstrates the wide variety of psychiatric comorbidities with migraine. However, more research is needed to elucidate the neurocircuitry underlying the association between migraine and the comorbid psychiatric conditions and to determine the most effective treatment for migraine with psychiatric comorbidity.
引用
收藏
页码:741 / 749
页数:9
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