Nanoformulations of Nutraceuticals for Cancer Treatment

被引:7
|
作者
Illahi, Aroosa Fazal [1 ]
Muhammad, Faqir [1 ]
Akhtar, Bushra [1 ]
机构
[1] Univ Agr Faisalabad, Fac Vet Sci, Inst Pharm Physiol & Pharmacol, Faisalabad, Pakistan
来源
CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION | 2019年 / 29卷 / 05期
关键词
nutraceuticals; nanoformulations; cancer; SOLID LIPID NANOPARTICLES; GREEN TEA CATECHIN; CELL LUNG-CANCER; IN-VITRO; CHITOSAN NANOPARTICLES; DRUG-DELIVERY; COLON-CANCER; BIODEGRADABLE NANOPARTICLES; POLYMERIC NANOPARTICLES; TUMOR MICROENVIRONMENT;
D O I
10.1615/CritRevEukaryotGeneExpr.2019025957
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Nutraceuticals are the bioactive chemical compounds, obtained from natural sources, having profound pharmacological activities. The well known phyto-ingredients with fantastic anticancer potential (e.g., curcumin, resveratrol, quercetin, genistein, and epigallocatechin gallate) have been encapsulated in biocompatible and biodegradable polymeric nanoparticles. Currently, anticancer nutraceuticals loaded in biodegradable polymeric nanoparticles demonstrate extraordinary results, revealing maximum solubility, absorption, bioavailability, and anticancer potential in comparison to nutraceuticals alone or in other drug delivery systems. Among these nutraceuticals, curcumin has been extensively studied and established as having optimal anticancer effects after integration in biocompatible and biodegradable polymeric nanoparticles.
引用
收藏
页码:449 / 460
页数:12
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