Sirtuins at a glance

被引：239

作者：

Nakagawa, Takashi ^{[1
]}

Guarente, Leonard ^{[1
]}

机构：

[1] MIT, Dept Biol, Paul F Glenn Lab Sci Aging, Cambridge, MA 02139 USA

来源：

JOURNAL OF CELL SCIENCE | 2011年 / 124卷 / 06期

关键词：

ACETYL-COA SYNTHETASE; FATTY-ACID OXIDATION; GENE-EXPRESSION; MAMMALIAN SIR2; GLUCOSE-HOMEOSTASIS; HISTONE DEACETYLASE; INSULIN-SECRETION; METABOLIC DISEASE; INCREASED DOSAGE; CELL-SURVIVAL;

D O I：

10.1242/jcs.081067

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

[No abstract available]

引用

页码：833 / 838

页数：6

共 90 条

[81] hSIR2SIRT1 functions as an NAD-dependent p53 deacetylase [J].

Vaziri, H ;

Dessain, SK ;

Eagon, EN ;

Imai, SI ;

Frye, RA ;

Pandita, TK ;

Guarente, L ;

Weinberg, RA .

CELL, 2001, 107 (02) :149-159

[82] Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice [J].

Wang, Rui-Hong ;

Sengupta, Kundan ;

Li, Cuiling ;

Kim, Hyun-Seok ;

Cao, Liu ;

Xiao, Cuiying ;

Kim, Sangsoo ;

Xu, Xiaoling ;

Zheng, Yin ;

Chilton, Beverly ;

Jia, Rong ;

Zheng, Zhi-Ming ;

Appella, Ettore ;

Wang, Xin Wei ;

Ried, Thomas ;

Deng, Chu-Xia .

CANCER CELL, 2008, 14 (04) :312-323

[83] Stress-Inducible Regulation of Heat Shock Factor 1 by the Deacetylase SIRT1 [J].

Westerheide, Sandy D. ;

Anckar, Julius ;

Stevens, Stanley M., Jr. ;

Sistonen, Lea ;

Morimoto, Richard I. .

SCIENCE, 2009, 323 (5917) :1063-1066

[84] SIRT6 Deficiency Results in Severe Hypoglycemia by Enhancing Both Basal and Insulin-stimulated Glucose Uptake in Mice [J].

Xiao, Cuiying ;

Kim, Hyun-Seok ;

Lahusen, Tyler ;

Wang, Rui-Hong ;

Xu, Xiaoling ;

Gavrilova, Oksana ;

Jou, William ;

Gius, David ;

Deng, Chu-Xia .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 285 (47) :36776-36784

[85] Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival [J].

Yang, Hongying ;

Yang, Tianle ;

Baur, Joseph A. ;

Perez, Evelyn ;

Matsui, Takashi ;

Carmona, Juan J. ;

Lamming, Dudley W. ;

Souza-Pinto, Nadja C. ;

Bohr, Vilhelm A. ;

Rosenzweig, Anthony ;

de Cabo, Rafael ;

Sauve, Anthony A. ;

Sinclair, David A. .

CELL, 2007, 130 (06) :1095-1107

[86] Modulation of NF-κB-dependent transcription and cell survival by the SIRT1 deacetylase [J].

Yeung, F ;

Hoberg, JE ;

Ramsey, CS ;

Keller, MD ;

Jones, DR ;

Frye, RA ;

Mayo, MW .

EMBO JOURNAL, 2004, 23 (12) :2369-2380

[87] Negative regulation of the deacetylase SIRT1 by DBC1 [J].

Zhao, Wenhui ;

Kruse, Jan-Philipp ;

Tang, Yi ;

Jung, Sung Yun ;

Qin, Jun ;

Gu, Wei .

NATURE, 2008, 451 (7178) :587-U11

[88] The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α [J].

Zhong, Lei ;

D'Urso, Agustina ;

Toiber, Debra ;

Sebastian, Carlos ;

Henry, Ryan E. ;

Vadysirisack, Douangsone D. ;

Guimaraes, Alexander ;

Marinelli, Brett ;

Wikstrom, Jakob D. ;

Nir, Tomer ;

Clish, Clary B. ;

Vaitheesvaran, Bhavapriya ;

Iliopoulos, Othon ;

Kurland, Irwin ;

Dor, Yuval ;

Weissleder, Ralph ;

Shirihai, Orian S. ;

Ellisen, Leif W. ;

Espinosa, Joaquin M. ;

Mostoslavsky, Raul .

CELL, 2010, 140 (02) :280-293

[89] SIRT1 Genetic Variation Is Related to BMI and Risk of Obesity [J].

Zillikens, M. Carola ;

van Meurs, Joyce B. J. ;

Rivadeneira, Fernando ;

Amin, Najaf ;

Hofman, Albert ;

Oostra, Ben A. ;

Sijbrands, Eric J. G. ;

Wittentan, Jacqueline C. M. ;

Pols, Huibert A. P. ;

van Duijn, Cornelia M. ;

Uitterlinden, Andre G. .

DIABETES, 2009, 58 (12) :2828-2834

[90] SIRT1 genetic variation and mortality in type 2 diabetes: interaction with smoking and dietary niacin [J].

Zillikens, M. Carola ;

van Meurs, Joyce B. J. ;

Sijbrands, Eric J. G. ;

Rivadeneira, Fernando ;

Dehghan, Abbas ;

van Leeuwen, Johannes P. T. M. ;

Hofman, Albert ;

van Duijn, Cornelia M. ;

Witteman, Jacqueline C. M. ;

Uitterlinden, Andre G. ;

Pols, Huibert A. P. .

FREE RADICAL BIOLOGY AND MEDICINE, 2009, 46 (06) :836-841

← 1 2 3 4 5 6 7 8 9 →