Insulin-lowering drugs in polycystic ovary syndrome

被引：50
作者：
Iuorno, MJ [1 ]
Nestler, JE [1 ]
机构：
[1] Virginia Commonwealth Univ, Med Coll Virginia, Dept Med, Div Endocrinol & Metab, Richmond, VA 23298 USA
来源：
OBSTETRICS AND GYNECOLOGY CLINICS OF NORTH AMERICA | 2001年 / 28卷 / 01期
关键词：
D O I：
10.1016/S0889-8545(05)70191-1
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Insulin resistance is now a recognized feature of polycystic ovary syndrome (PCOS) that plays a crucial role in the hyperandrogenemia and chronic anovulation associated with this disorder. As a result of this discovery, insulin sensitizing drugs are emerging as important therapeutic tools that appear to reduce androgens and insulin, thereby ameliorating reproductive and metabolic abnormalities of PCOS. Unlike conventional therapies for PCOS, these drugs offer the ability to reverse or ameliorate features of syndrome X. The latter suggests that insulin sensitizing drugs may play a role in the chronic management of this disorder.
引用
收藏
页码：153 / +
页数：13
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