Vascular Endothelial Growth Factor and Its Type 2 Receptor in Hepatocellular Carcinoma

被引：20

作者：

Gershtein, E. S. ^{[1
]}

Dubova, E. A. ^{[2
]}

Shchegolev, A. I. ^{[2
]}

Kushkinskii, N. E. ^{[1
]}

机构：

[1] Russian Acad Med Sci, NN Blokhin Canc Res Ctr, Moscow, Russia

[2] Fed Agcy Med Technol, VI Kulakov Res Ctr Obstet Gynecol & Perinatol, Moscow, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2010年 / 149卷 / 06期

关键词：

angiogenesis; hepatocellular carcinoma; vascular endothelial growth factor; type 2 vascular endothelial growth factor receptor; ANGIOGENESIS; VEGF; EXPRESSION;

D O I：

10.1007/s10517-010-1043-8

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Histological analysis demonstrated an increase in the number of blood vessels and expression of CD34 and vascular endothelial growth factor in hepatocellular carcinoma tissue compared to adjacent liver tissue. Increased immunohistochemical expression of vascular endothelial growth factor and the content of this factor and its type 2 receptor correlated with the degree of histological differentiation and stage of the tumor.

引用

页码：749 / 752

页数：4

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