Risk Factors of Hepatocellular Carcinoma - Current Status and Perspectives

被引:109
作者
Gao, Jing [1 ,2 ]
Xie, Li [1 ,2 ]
Yang, Wan-Shui [1 ,2 ]
Zhang, Wei [1 ,2 ]
Gao, Shan [3 ]
Wang, Jing [1 ,2 ]
Xiang, Yong-Bing [1 ,2 ]
机构
[1] Shanghai Jiao Tong Univ, Sch Med, State Key Lab Oncogene & Related Genes, Shanghai Canc Inst,Renji Hosp, Shanghai 200030, Peoples R China
[2] Shanghai Jiao Tong Univ, Sch Med, Dept Epidemiol, Shanghai Canc Inst,Renji Hosp, Shanghai 200030, Peoples R China
[3] Zhengzhou Univ, Affiliated Hosp 1, Dept Infect Management, Zhengzhou, Peoples R China
关键词
Hepatocellular carcinoma; risk factors; epidemiology; PRIMARY LIVER-CANCER; HEPATITIS-B-VIRUS; ORAL-CONTRACEPTIVE USE; C VIRUS; ALCOHOL-CONSUMPTION; CIGARETTE-SMOKING; UNITED-STATES; VIRAL-HEPATITIS; IRON OVERLOAD; FOLLOW-UP;
D O I
10.7314/APJCP.2012.13.3.743
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Hepatocellular carcinoma is a common disorder worldwide which ranks 5th and 7th most common cancer among men and women. In recent years, different incidence trends have been observed in various regions, but the reasons are not completely understood. However, due to the great public efforts in HCC prevention and alternation of lifestyle, the roles of some well documented risk factors played in hepatocarcinogenesis might have changed. This paper summarizes both the environmental and host related risk factors of hepatocellular carcinoma including well established risk factors such as hepatitis virus infection, aflatoxin and alcohol, as well as possible risk factors such as coffee drinking and other dietary agents.
引用
收藏
页码:743 / 752
页数:10
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