Ramipril-associated lichen planus pemphigoides

被引：15
|
作者：
Ogg, GS
Bhogal, BS
Hashimoto, T
Coleman, R
Barker, JNWN
机构：
[1] ST THOMAS HOSP,ST JOHNS INST DERMATOL,LONDON SE1 7EH,ENGLAND
[2] KEIO UNIV,SCH MED,DEPT DERMATOL,SHINJUKU KU,TOKYO 160,JAPAN
来源：
BRITISH JOURNAL OF DERMATOLOGY | 1997年 / 136卷 / 03期
关键词：
D O I：
10.1046/j.1365-2133.1997.5761550.x
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
We report the first case of lichen planus pemphigoides (LPP) secondary to ingestion of ramipril, an angiotensin-converting enzyme inhibitor. Clinical, histological and immunofluorescent findings were all consistent with a diagnosis of LPP. Linear basement membrane zone (BMZ) staining with IgG and C3 was only seen at the roof of split-skin preparations and circulating autoantibody to the BMZ was present at a titre of 1/100. Controlled immunoblotting of epidermal extracts detected the bullous pemphigoid antigens of 230 and 1.80 kDa.
引用
收藏
页码：412 / 414
页数：3
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