Ramipril-associated lichen planus pemphigoides

被引：18

作者：

Ogg, GS

Bhogal, BS

Hashimoto, T

Coleman, R

Barker, JNWN

机构：

[1] ST THOMAS HOSP,ST JOHNS INST DERMATOL,LONDON SE1 7EH,ENGLAND

[2] KEIO UNIV,SCH MED,DEPT DERMATOL,SHINJUKU KU,TOKYO 160,JAPAN

来源：

BRITISH JOURNAL OF DERMATOLOGY | 1997年 / 136卷 / 03期

关键词：

D O I：

10.1046/j.1365-2133.1997.5761550.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We report the first case of lichen planus pemphigoides (LPP) secondary to ingestion of ramipril, an angiotensin-converting enzyme inhibitor. Clinical, histological and immunofluorescent findings were all consistent with a diagnosis of LPP. Linear basement membrane zone (BMZ) staining with IgG and C3 was only seen at the roof of split-skin preparations and circulating autoantibody to the BMZ was present at a titre of 1/100. Controlled immunoblotting of epidermal extracts detected the bullous pemphigoid antigens of 230 and 1.80 kDa.

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收藏

页码：412 / 414

页数：3

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