Apnea and its possible relationship to immunization in ex-premature infants

被引：13

作者：

Cooper, Peter A. ^{[2
]}

Madhi, Shabir A. ^{[1
,3
]}

Huebner, Robin E. ^{[1
,3
]}

Mbelle, Nontombi ^{[1
,3
]}

Karim, Salim S. Abdool ^{[4
]}

Kleinschmidt, Immo

Forrest, Bruce D. ^{[5
]}

Klugman, Keith P. ^{[1
,3
,6
,7
]}

机构：

[1] Univ Witwatersrand, Natl Res Fdn Vaccine Preventable Dis, Dept Sci & Technol, Chris Hani Baragwanath Hosp, ZA-2013 Bertsham, South Africa

[2] Univ Witwatersrand, Dept Paediat, ZA-2013 Bertsham, South Africa

[3] Univ Witwatersrand, Resp & Meningeal Pathogens Res Unit, ZA-2013 Bertsham, South Africa

[4] Univ KwaZulu Natal, Durban, South Africa

[5] Wyeth Vaccines Res Clin Res, Pearl River, NY USA

[6] Emory Univ, Sch Med, Hubert Dept Global Hlth, Rollins Sch Publ Hlth, Atlanta, GA USA

[7] Emory Univ, Sch Med, Div Infect Dis, Atlanta, GA USA

来源：

VACCINE | 2008年 / 26卷 / 27-28期

基金：

英国医学研究理事会;

关键词：

vaccines; apnea; premature; infants;

D O I：

10.1016/j.vaccine.2008.04.037

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

This study compared the characteristics of infants hospitalized with apnea that participated in a vaccine trial compared with two control groups which consisted of 100 infants randomly selected from the same vaccine trial and 52 consecutively born very low birth weight (VLBW) infants. A total of 23 infants were admitted with apnea of whom 19 weighed <1 500 g at birth and all were born at <37 weeks gestation. More of the VL13VV infants in the apnea group had neonatal neurological complications compared with the VLBW control group (p = 0.005). Ten of 11 children with apnea within 72 h of immunization were possibly related to vaccination. (c) 2008 Elsevier Ltd. All rights reserved.

引用

页码：3410 / 3413

页数：4

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