A genome scan for QTL affecting fleece and wool traits in Merino sheep

被引：0

作者：

Beh, KJ ^{[1
]}

Callaghan, MJ ^{[1
]}

Leish, Z ^{[1
]}

Hulme, DJ ^{[1
]}

Lenane, I ^{[1
]}

Maddox, JF ^{[1
]}

机构：

[1] CSIRO, Livestock Ind, Blacktown, NSW 2148, Australia

来源：

WOOL TECHNOLOGY AND SHEEP BREEDING | 2001年 / 49卷 / 02期

关键词：

sheep; wool; quantitative trait loci; genome;

D O I：

暂无

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

A whole genome scan for quantitative trait loci (QTL) affecting 11 fleece and wool traits was carried out in a flock of medium wool Merino sheep. The flock consisted of 489, sheep in 5 sire groups with family sizes ranging from 59 to 139 offspring. On average 73% of the animals in each family were genotyped with a panel of 130 microsatellite markers, spread throughout the genome. Interval analysis of the data revealed 18 peaks with maximum logarithm of the odds scores (LOD) greater than or equal to 2. Critical P-values for QTL detection, accounting for the large number of hypotheses tested, were estimated by calculating the expected false discovery rate (FDR). For the distribution of LOD score peaks found the FDR always exceeded 0.65 indicating that little evidence was found against all null hypotheses of no QTL present. Evidence for a QTL affecting mean fibre diameter (LOD=2.01) was found on chromosome 1 in agreement with previously reported results of a candidate gene study. The results of the present study may be useful to indicate, chromosomal segments on which to concentrate future genotyping for QTL although the conservative conclusion that must be drawn is that no significant evidence for the segregation of fleece and wool QTL was found in this flock.

引用

页码：88 / 97

页数：10

共 26 条

[1]

Beh KJ, 1998, ICOPA IX - 9TH INTERNATIONAL CONGRESS OF PARASITOLOGY, P563

[2]

BEH KJ, 2001, UNPUB ANIMAL GENETIC

[3] INHERITANCE OF A MAJOR GENE FOR EXCESSIVELY LUSTROUS WOOL IN SHEEP [J].