Markers of oxidative stress before and after exchange transfusion for neonatal sepsis

被引:0
|
作者
Kokk, T
Talvik, R
Zilmer, M
Kutt, E
Talvik, T
机构
[1] TARTU STATE UNIV,CHILDRENS HOSP,CLIN ANAESTHESIOL & INTENS CARE,INTENS CARE UNIT,EE-2400 TARTU,ESTONIA
[2] TARTU STATE UNIV,DEPT BIOCHEM,EE-2400 TARTU,ESTONIA
关键词
antioxidants; exchange transfusion; newborn; oxidative stress; sepsis;
D O I
暂无
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Oxidative status before and after ET was assessed in eight septic newborns who received exchange transfusion (ET. Short-term elevations of conjugated dienes (CDs) and thiobarbituric acid reactive substances (TBARSs) (p < 0.05) and increased serum antioxidant capacity (AOC) (p = 0.06) were noted. Chromatographic migration of the red blood cells (CM RBCs), a measure of RBC deformability, also improved after ET. ET for neonatal sepsis does not cause significant oxidative stress. rather, it may help to restore the antioxidant depots and improve RBC deformability and microcirculation.
引用
收藏
页码:1244 / 1246
页数:3
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