Resolution of renal allograft-associated post-transplant lymphoproliferative disorder with the introduction of sirolimus

被引:21
作者
Zaltzman, JS
Prasad, R
Chun, K
Jothy, S
机构
[1] Univ Toronto, St Michaels Hosp, Div Nephrol, Toronto, ON M5B 1W8, Canada
[2] St Michaels Hosp, Dept Lab Med & Pathobiol, Toronto, ON M5B 1W8, Canada
[3] Univ Toronto, Univ Hlth Network, Dept Pathol, Toronto, ON, Canada
关键词
post-transplant lymphoproliferative disorder; sirolimus;
D O I
10.1093/ndt/gfh884
中图分类号
R3 [基础医学]; R4 [临床医学];
学科分类号
1001 ; 1002 ; 100602 ;
摘要
In summary, this case demonstrated a very rapid development of PTLD, which did not respond to reduction in immunosuppressive therapy and antiviral therapy, but did resolve with the administration of sirolimus. The mTOR inhibitors may be of benefit in the prevention and treatment in PTLD in recipients of solid organ allografts. © The Author [2005]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved.
引用
收藏
页码:1748 / 1751
页数:4
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