Duchenne Muscular Dystrophy Successfully Treated with Aripiprazole in a Patient with Autism Spectrum Disorder Symptoms Including Irritability

被引：3

作者：

Noda, Seiya ^{[1
,2
]}

Murakami, Ayuka ^{[1
,2
]}

Kimura, Seigo ^{[1
,2
]}

Minamiyama, Makoto ^{[2
]}

Katsuno, Masahisa ^{[1
]}

Kuru, Satoshi ^{[2
]}

机构：

[1] Nagoya Univ, Dept Neurol, Grad Sch Med, Nagoya, Aichi, Japan

[2] Natl Hosp Org, Dept Neurol, Suzuka Hosp, Suzuka, Japan

来源：

INTERNAL MEDICINE | 2021年 / 60卷 / 24期

关键词：

Duchenne muscular dystrophy; aripiprazole; autism spectrum disorder; irritability; CHILDREN; GENE; METAANALYSIS; ADOLESCENTS; MUTATIONS; RECEPTORS; EFFICACY; BEHAVIOR; SAFETY;

D O I：

10.2169/internalmedicine.7248-21

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Duchenne muscular dystrophy (DMD) is associated with neuropsychiatric disorders, and patients often present with autism spectrum disorder (ASD). We herein report a case of DMD accompanied by ASD that was successfully treated with aripiprazole, an atypical antipsychotic that has been used for treating irritability in child and early adolescent patients with ASD. The patient was diagnosed as having DMD at 3 years of age. Although he developed severe psychotic symptoms including irritability, insomnia, hallucinations, and delusions at 17 years of age, all the symptoms were successfully treated with aripiprazole without any detectable side effects.

引用

页码：3983 / 3986

页数：4

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