Pediatric meningioma: current approaches and future direction

被引：63

作者：

Kotecha, Rishi S. ^{[1
,2
,3
,4
]}

Junckerstorff, Reimar C. ^{[5
]}

Lee, Sharon ^{[6
]}

Cole, Catherine H. ^{[1
,4
]}

Gottardo, Nicholas G. ^{[1
,2
,3
,4
]}

机构：

[1] Princess Margaret Hosp Children, Dept Hematol & Oncol, Perth, WA 6840, Australia

[2] Univ Western Australia, Telethon Inst Child Hlth Res, Perth, WA 6009, Australia

[3] Univ Western Australia, Ctr Child Hlth Res, Perth, WA 6009, Australia

[4] Univ Western Australia, Sch Pediat & Child Hlth, Perth, WA 6009, Australia

[5] Royal Perth Hosp, PathW Lab Med, Sect Neuropathol, Perth, WA, Australia

[6] Princess Margaret Hosp Children, Dept Neurosurg, Perth, WA, Australia

来源：

JOURNAL OF NEURO-ONCOLOGY | 2011年 / 104卷 / 01期

关键词：

Pediatric; Meningioma; Clinical review; OF-THE-LITERATURE; RADIATION-INDUCED MENINGIOMAS; PROGESTERONE-RECEPTOR STATUS; INTRACRANIAL MENINGIOMAS; IMMUNOHISTOCHEMICAL EXPRESSION; MENINGEAL TUMORS; HISTOPATHOLOGIC FINDINGS; ANAPLASTIC MENINGIOMAS; CHILDHOOD MENINGIOMAS; ESTROGEN-RECEPTORS;

D O I：

10.1007/s11060-010-0503-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

With improvement in leukemia therapy, central nervous system (CNS) tumors are the leading cause of cancer mortality in children and the most expensive of all human neoplasms to treat. Meningiomas are rare intracranial tumors in childhood and adolescence arising from arachnoid cell clonal outgrowth in the meninges. There have been no collaborative prospective therapeutic trials for pediatric meningioma because of its rarity, and the best evidence for management comes from retrospective case analyses and extrapolation from the treatment of adult meningioma. However this may not be ideal, because the underlying biology of adult and pediatric meningiomas seems to be different, as is the case for other CNS tumors. In addition, treatment of pediatric brain tumors requires consideration of long-term quality of life. This review reflects on what is currently known about pediatric meningiomas and opportunities for future directions.

引用

页码：1 / 10

页数：10

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