Determination of the spatial structure of glutathione by residual dipolar coupling analysis

被引：16
|
作者：
Klochkov, AV [1 ]
Khairutdinov, BI [1 ]
Tagirov, MS [1 ]
Klochkov, VV [1 ]
机构：
[1] Kazan VI Lenin State Univ, Dept Phys, Kazan 420008, Russia
来源：
MAGNETIC RESONANCE IN CHEMISTRY | 2005年 / 43卷 / 11期
关键词：
NMR; H-1; C-13; residual dipolar couplings; spatial structure; lyotropic medium; gamma-L-glutamyl-L-cysteinylglycine; cetylpyridinium chloride;
D O I：
10.1002/mrc.1650
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The approach based on analysis of the residual H-1-C-13 dipolar couplings in molecules partially aligned in a lyotropic liquid crystalline medium was used in the NMR investigation of the reduced glutathione (Glu-Cys-Gly; GSH) structure in a lyotropic medium (cetylpyridinium chloride-n-hexanol). The spatial structure of GSH in solution was established on the basis of the experimental data for observed couplings only. Copyright (c) 2005 John Wiley & Sons, Ltd.
引用
收藏
页码：948 / 951
页数：4
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