Determination of the spatial structure of glutathione by residual dipolar coupling analysis

被引：16
|
作者：
Klochkov, AV [1 ]
Khairutdinov, BI [1 ]
Tagirov, MS [1 ]
Klochkov, VV [1 ]
机构：
[1] Kazan VI Lenin State Univ, Dept Phys, Kazan 420008, Russia
来源：
MAGNETIC RESONANCE IN CHEMISTRY | 2005年 / 43卷 / 11期
关键词：
NMR; H-1; C-13; residual dipolar couplings; spatial structure; lyotropic medium; gamma-L-glutamyl-L-cysteinylglycine; cetylpyridinium chloride;
D O I：
10.1002/mrc.1650
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The approach based on analysis of the residual H-1-C-13 dipolar couplings in molecules partially aligned in a lyotropic liquid crystalline medium was used in the NMR investigation of the reduced glutathione (Glu-Cys-Gly; GSH) structure in a lyotropic medium (cetylpyridinium chloride-n-hexanol). The spatial structure of GSH in solution was established on the basis of the experimental data for observed couplings only. Copyright (c) 2005 John Wiley & Sons, Ltd.
引用
收藏
页码：948 / 951
页数：4
相关论文
共 50 条
  • [1] Spatial structure of triglycine determined by the residual dipolar coupling analysis
    V. V. Klochkov
    B. I. Khairutdinov
    A. V. Klochkov
    V. G. Shtyrlin
    R. A. Shaykhutdinov
    Applied Magnetic Resonance, 2003, 25 : 113 - 119
  • [2] Spatial structure of triglycine determined by the residual dipolar coupling analysis
    Klochkov, VV
    Khairutdinov, BI
    Klochkov, AV
    Shtyrlin, VG
    Shaykhutdinov, RA
    APPLIED MAGNETIC RESONANCE, 2003, 25 (01) : 113 - 119
  • [3] Residual dipolar coupling constants and structure determination of large DNA duplexes
    Mauffret, O
    Tevanian, G
    Fermandjian, S
    JOURNAL OF BIOMOLECULAR NMR, 2002, 24 (04) : 317 - 328
  • [4] Residual dipolar coupling constants and structure determination of large DNA duplexes
    Olivier Mauffret
    Georges Tevanian
    Serge Fermandjian
    Journal of Biomolecular NMR, 2002, 24 : 317 - 328
  • [5] Spatial structure of peptides determined by residual dipolar couplings analysis
    Klochkov, Vladimir V.
    Baikeev, Roustern F.
    Skirda, Vladimir D.
    Klochkov, Anton V.
    Muhamadiev, Farhat R.
    Baskyr, Igor
    Berger, Stefan
    MAGNETIC RESONANCE IN CHEMISTRY, 2009, 47 (01) : 57 - 62
  • [6] Refinement of the structure of protein–RNA complexes by residual dipolar coupling analysis
    Peter Bayer
    Luca Varani
    Gabriele Varani
    Journal of Biomolecular NMR, 1999, 14 : 149 - 155
  • [7] Residual dipolar couplings in structure determination of biomolecules
    Prestegard, JH
    Bougault, CM
    Kishore, AI
    CHEMICAL REVIEWS, 2004, 104 (08) : 3519 - 3540
  • [8] REDCAT: a residual dipolar coupling analysis tool
    Valafar, H
    Prestegard, JH
    JOURNAL OF MAGNETIC RESONANCE, 2004, 167 (02) : 228 - 241
  • [9] Refinement of the structure of protein-RNA complexes by residual dipolar coupling analysis
    Bayer, P
    Varani, L
    Varani, G
    JOURNAL OF BIOMOLECULAR NMR, 1999, 14 (02) : 149 - 155
  • [10] The use of a lyotropic liquid-crystalline medium and residual dipolar coupling constants for determination of the spatial structure of thiacalix[4]arenes in solutions
    V. V. Klochkov
    B. I. Khairutdinov
    A. V. Klochkov
    M. S. Tagirov
    C. M. Thiele
    S. Berger
    I. S. Vershinina
    I. I. Stoikov
    I. S. Antipin
    A. I. Konovalov
    Russian Chemical Bulletin, 2004, 53 : 1466 - 1470
12345