Studies on electrochemical oxidation mechanisms of polyamides containing N-methylpyrrole and N-methylimidazole by electrospray ionization tandem mass spectrometry

被引：4
作者：
Ji, ZH
Li, JJ [1 ]
Zhou, J
Hui, LM
Yuan, G
Cai, SM
机构：
[1] Peking Univ, Coll Chem, Beijing 100871, Peoples R China
[2] Peking Univ, Dept Biol Chem, Key Lab Bioorgan Chem & Mol Engn, Minist Educ, Beijing 100871, Peoples R China
来源：
JOURNAL OF PHYSICAL CHEMISTRY B | 2005年 / 109卷 / 36期
关键词：
D O I：
10.1021/jp045277q
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Electrochemical oxidization mechanism of polyamides containing N-methylpyrrole and N-methylimidazole was investigated by electrospray ionization tandem mass spectrometry (ESI-MSn). The spectra of the oxidization products unambiguously revealed that one or two oxygen atoms are added to the polyamide after the bulk electrolysis. It was found that electrochemical oxidation preferably takes place on the imidazole ring of the polyamide with both imidazole and pyrrole to produce a carbonyl group on the rings. ESI tandem mass spectrometry has proven to be an excellent method for the structural identification of electrochemical oxidation products of DNA-recognizing polyamides.
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收藏
页码：17162 / 17168
页数：7
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