Novel electrospun polycaprolactone/graphene oxide/Fe3O4 nanocomposites for biomedical applications

被引:39
作者
Aydogdu, Mehmet Onur [1 ,2 ]
Ekren, Nazmi [1 ,3 ]
Suleymanoglu, Mediha [4 ]
Erdem-Kuruca, Serap [4 ]
Lin, Chi-Chang [5 ]
Bulbul, Ertugrul [1 ]
Erdol, Meltem Nur [6 ]
Oktar, Faik Nuzhet [1 ,6 ]
Terzi, Umit Kemalettin [3 ]
Kilic, Osman [7 ]
Gunduz, Oguzhan [1 ,8 ]
机构
[1] Marmara Univ, Dept Met & Mat Engn, Adv Nanomat Res Lab, Goztepe Campus, TR-34722 Istanbul, Turkey
[2] Marmara Univ, Inst Pure & Appl Sci, Dept Met & Mat Engn, Sci, Goztepe Campus, TR-34722 Istanbul, Turkey
[3] Marmara Univ, Fac Technol, Dept Elect Elect Engn, Goztepe Campus, TR-34722 Istanbul, Turkey
[4] Istanbul Univ, Sch Med, Dept Physiol, Istanbul, Turkey
[5] Tunghai Univ, Dept Chem & Mat Engn, Taichung, Taiwan
[6] Marmara Univ, Fac Engn, Dept Bioengn, Goztepe Campus, TR-34722 Istanbul, Turkey
[7] Marmara Univ, Fac Engn, Dept Elect & Elect Engn, Goztepe Campus, TR-34722 Istanbul, Turkey
[8] Marmara Univ, Fac Technol, Dept Met & Mat Engn, Goztepe Campus, TR-34722 Istanbul, Turkey
关键词
PCL; Graphene oxides; Electrospinning; Biomedical engineering; Electrical properties; GRAPHENE OXIDE; NANOFIBERS; TOXICITY; NANOPARTICLES; PERFORMANCE; FABRICATION; GROWTH;
D O I
10.1016/j.colsurfb.2018.09.035
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
In this study, one of the most promising methods of tailoring a composite scaffold material in nano sized diameters, electrospinning method were used to produce Polycaprolactone (PCL)/Graphene Oxide (GO)/Iron(II, III) Oxide (Fe3O4) nanocomposite fibers as biocompatible scaffolds for biomedical applications. Products were analyzed by scanning electron microscopy (SEM) for morphological analysis of the electrospun nanocomposites and Fourier Transform Infrared Spectroscopy (FTIR) was used to determine functional groups of the PCL, GO, and Fe3O4 materials in the electrospun nanocomposites. For physical properties, viscosity, density, permittivity, dielectric loss and liquid and solid state alternating current conductivity, measurements were done for each nanocomposite fibers. Effects of concentration percentage of GO on permittivity, dielectric loss and AC conductivity have been analyzed by using measured and calculated data. Trend lines have been drawn for permittivity, dielectric loss and conductivity via concentration percentage of GO. The relation between ac conductivity and frequency have been studied for each concentration percentage of GO and interpretations have been done by using the obtained results.
引用
收藏
页码:718 / 727
页数:10
相关论文
共 36 条
[1]   Production of the biomimetic small diameter blood vessels for cardiovascular tissue engineering [J].
Aydogdu, Mehmet Onur ;
Chou, Joshua ;
Altun, Esra ;
Ekren, Nazmi ;
Cakmak, Selami ;
Eroglu, Mehmet ;
Osman, Asila A. ;
Kutlu, Ozlem ;
Oner, Ebru Toksoy ;
Avsar, Gulben ;
Oktar, Faik Nuzhet ;
Yilmaz, Ismail ;
Gunduz, Oguzhan .
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS, 2019, 68 (05) :243-255
[2]   Dielectric characterization of NixCo1-xFe2O4 nanocrystals thin film over a broad frequency range (1 MHz-3 GHz) [J].
Bayrakdar, Harun ;
Esmer, Kadir .
JOURNAL OF APPLIED PHYSICS, 2010, 107 (04)
[3]   Nanofibrous materials and their applications [J].
Burger, Christian ;
Hsiao, Benjamin S. ;
Chu, Benjamin .
ANNUAL REVIEW OF MATERIALS RESEARCH, 2006, 36 :333-368
[4]   Enhancing mechanical properties of polyelectrolyte complex nanofibers with graphene oxide nanofillers pretreated by polycation [J].
Cai, Ning ;
Hou, Dajun ;
Luo, Xiaogang ;
Han, Chao ;
Fu, Jing ;
Zeng, Huan ;
Yu, Faquan .
COMPOSITES SCIENCE AND TECHNOLOGY, 2016, 135 :128-136
[5]   In vitro toxicity evaluation of graphene oxide on A549 cells [J].
Chang, Yanli ;
Yang, Sheng-Tao ;
Liu, Jia-Hui ;
Dong, Erya ;
Wang, Yanwen ;
Cao, Aoneng ;
Liu, Yuanfang ;
Wang, Haifang .
TOXICOLOGY LETTERS, 2011, 200 (03) :201-210
[6]   The Toxicity of Graphene Oxides: Dependence on the Oxidative Methods Used [J].
Chng, Elaine Lay Khim ;
Pumera, Martin .
CHEMISTRY-A EUROPEAN JOURNAL, 2013, 19 (25) :8227-8235
[7]   Spatially resolved raman spectroscopy of single- and few-layer graphene [J].
Graf, D. ;
Molitor, F. ;
Ensslin, K. ;
Stampfer, C. ;
Jungen, A. ;
Hierold, C. ;
Wirtz, L. .
NANO LETTERS, 2007, 7 (02) :238-242
[8]   One pot preparation of reduced graphene oxide (RGO) or Au (Ag) nanoparticle-RGO hybrids using chitosan as a reducing and stabilizing agent and their use in methanol electrooxidation [J].
Guo, Yongqin ;
Sun, Xiying ;
Liu, Yu ;
Wang, Wei ;
Qiu, Haixia ;
Gao, Jianping .
CARBON, 2012, 50 (07) :2513-2523
[9]   BMP-2 Grafted nHA/PLGA Hybrid Nanofiber Scaffold Stimulates Osteoblastic Cells Growth [J].
Haider, Adnan ;
Kim, Sukyoung ;
Huh, Man-Woo ;
Kang, Inn-Kyu .
BIOMED RESEARCH INTERNATIONAL, 2015, 2015
[10]   Biogenic synthesis of iron nanoparticles using Amaranthus dubius leaf extract as a reducing agent [J].
Harshiny, Muthukumar ;
Iswarya, Chandrasekaran Nivedhini ;
Matheswaran, Manickam .
POWDER TECHNOLOGY, 2015, 286 :744-749