Maternal and cord blood cyclophilin A in severe preeclampsia and normal pregnancy and its correlation with vitamin D and zinc

被引：14
|
作者：
Wibowo, Noroyono [1 ]
Kurniawan, Riyan Hari [2 ]
Irwinda, Rima [1 ]
Prameswari, Natasya [2 ]
机构：
[1] Univ Indonesia, Cipto Mangunkusumo Hosp, Dept Obstet & Gynecol, Fetomaternal Div,Fac Med, Jakarta, Indonesia
[2] Univ Indonesia, Cipto Mangunkusumo Hosp, Dept Obstet & Gynecol, Fac Med, Jakarta, Indonesia
来源：
HYPERTENSION IN PREGNANCY | 2017年 / 36卷 / 04期
关键词：
Cyclophilin A; CyPA; vitamin D; zinc; severe preeclampsia; LEVEL; CALCIUM; CD147; IRON; RISK;
D O I：
10.1080/10641955.2017.1385792
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Objective: To investigate maternal and cord blood cyclophilin A level in severe preeclampsia compared with normal pregnancy and its correlation with vitamin D and zinc level.Methods: We conducted a cross-sectional observational study of pregnant women who gave birth in Cipto Mangunkusumo Hospital between January and April 2014.Results: Thirty-nine subjects were included. Subjects with severe preeclampsia have higher serum cyclophilin A levels compared with normotensive pregnancy (1299.60 vs. 1039.50; p 0.017). Maternal cyclophilin A, vitamin D, and zinc correlation were not statistically significant (p 0.189 & p 0.853).Conclusion: Cyclophilin A levels in severe preeclampsia is higher compared to normal pregnancy. There is no correlation between cyclophilin A, zinc, and vitamin D.
引用
收藏
页码：283 / 287
页数：5
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