Auraptene and Its Role in Chronic Diseases

被引：22

作者：

Derosa, Giuseppe ^{[1
,2
,3
,4
]}

Maffioli, Pamela ^{[1
,2
,5
]}

Sahebkar, Amirhossein ^{[6
,7
,8
]}

机构：

[1] Univ Pavia, Fdn IRCCS Policlin San Matteo, Dept Internal Med & Therapeut, Ple C Golgi 2, I-27100 Pavia, Italy

[2] Fdn IRCCS Policlin San Matteo, Ctr Prevent Surveillance Diag & Treatment Rare Di, Pavia, Italy

[3] Univ Pavia, Ctr Study Endocrine Metab Pathophysiol & Clin Res, Pavia, Italy

[4] Univ Pavia, Lab Mol Med, Pavia, Italy

[5] Univ Pavia, PhD Sch Expt Med, Pavia, Italy

[6] Mashhad Univ Med Sci, Biotechnol Res Ctr, Mashhad, Razavi Khorasan, Iran

[7] Univ Western Australia, Royal Perth Hosp, Metab Res Ctr, Sch Med & Pharmacol, Perth, WA, Australia

[8] Mashhad Univ Med Sci, Sch Med, Dept Med Biotechnol, POB 91779-48564, Mashhad, Razavi Khorasan, Iran

来源：

DRUG DISCOVERY FROM MOTHER NATURE | 2016年 / 929卷

关键词：

Auraptene; Chemoprevention; Degenerative diseases; Hypertension; Lipid profile; MONOTERPENE COUMARIN; CITRUS AURAPTENE; INFLAMMATION; METABOLISM; CHEMISTRY;

D O I：

10.1007/978-3-319-41342-6_19

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Auraptene (7-geranyloxycoumarin) is the best known and most abundant prenyloxycoumarin present in nature. It is synthesized by various plant species, mainly those of the Rutaceae and Umbeliferae (Apiaceae) families, comprising many edible fruits and vegetables such as lemons, grapefruit and orange. Auraptene has shown a remarkable effect in the prevention of degenerative diseases, in particular it has been reported to be one the most promising known natural chemopreventive agents against several types of cancer. The aim of this chapter is to review the effects of auraptene in the prevention and treatment of different chronic diseases.

引用

页码：399 / 407

页数：9

共 30 条

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