Aortic Arch Aneurysm in Behcet Disease Successfully Treated with Infliximab

被引:0
作者
Nishiyama, Taihei [1 ]
Kondo, Yuya [1 ]
Okamoto, Shota [1 ]
Terasaki, Mayu [1 ]
Toko, Hirofumi [1 ]
Yagishita, Mizuki [1 ]
Takahashi, Hiroyuki [1 ]
Yokosawa, Masahiro [1 ]
Tsuboi, Hiroto [1 ]
Matsumoto, Isao [1 ]
Sumida, Takayuki [1 ]
机构
[1] Univ Tsukuba, Fac Med, Dept Internal Med, Tsukuba, Ibaraki, Japan
关键词
Behcet disease; vascular Behcet disease; aortic arch aneurysm; infliximah; PULMONARY-ARTERY ANEURYSMS; NECROSIS-FACTOR-ALPHA; ANTI-TNF-ALPHA; VASCULAR INVOLVEMENT; LOCALIZATION; PATIENT;
D O I
10.2169/internalmedicine.3946-19
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aortic arch aneurysm (AAA) is a rare involvement in Behcet disease (BD). It is often life-threatening, yet few reports related to the treatment of AAA have been published. We herein report a 27-year-old woman with AAA caused by vascular BD. She was initially treated with prednisolone 1 mg/kg/d. However, the inflammation had not subsided after three weeks, so infliximab (IFX) was added for relief. After IFX administration, the C-reactive protein level normalized, and computed tomography at three months after therapeutic intervention revealed that the aneurysm had disappeared. This case suggests that early induction of IFX might be effective for aortic aneurysm in BD.
引用
收藏
页码:1087 / 1091
页数:5
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