Use of graphene-based materials as carriers of bioactive agents

被引：67
作者：
Lai, Wing-Fu [1 ,2 ]
Wong, Wing-Tak [2 ]
机构：
[1] Chinese Univ Hong Kong Shenzhen, Sch Life & Hlth Sci, Ciechanover Inst Precis & Regenerat Med, Shenzhen 518172, Peoples R China
[2] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Hong Kong, Peoples R China
来源：
ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES | 2021年 / 16卷 / 05期
关键词：
Graphene; Carbon; Nanomaterial; Loading; Controlled release; NUCLEIC-ACID DELIVERY; DRUG-DELIVERY; GENE DELIVERY; FUNCTIONALIZED GRAPHENE; QUANTUM DOTS; OXIDE-POLYETHYLENIMINE; CONTROLLED-RELEASE; TARGETED DELIVERY; CANCER-CELLS; EFFICIENT;
D O I：
10.1016/j.ajps.2020.11.004
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Graphene possesses a large specific surface area, a high Young's modulus, high fracture strength, high electrical conductivity, and excellent optical performance. It has been widely studied for biomedical use since its first appearance in the literature. This article offers an overview of the latest advances in the design of graphene-based materials for delivery of bioactive agents. To enhance the translation of these carriers into practical use, the toxicity involved is needed to be examined in future research in more detail. In addition, guidelines for standardizing experimental conditions during the evaluation of the performance of graphene-based materials are required to be established so that candidates showing higher practical potential can be more effectively identified for further development. This can streamline the optimization and use of graphene-based materials in delivery applications. (C) 2021 Published by Elsevier B.V. on behalf of Shenyang Pharmaceutical University.
引用
收藏
页码：577 / 588
页数：12
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