This article considers the increased focus on interdisciplinary research to solve major social problems through game changing solutions. It discusses research in the arts and humanities within the context of interdisciplinary research and within the broader academy. In particular, it distinguishes between research in the arts, and research in the humanities. More specifically, it goes on to consider an element within the arts known as design. In this context, the processes of design thinking across many disciplines are considered essential to the potential of interdisciplinary research to produce radical innovations.