Prevalence, Pharmacological Treatment, and Control of Cardiometabolic Risk Factors among Older People in Central Stockholm: A Population-Based Study

被引:19
作者
Wang, Rui [1 ]
Fratiglioni, Laura [1 ,2 ]
Liang, Yajun [1 ,3 ]
Welmer, Anna-Karin [1 ,4 ]
Xu, Weili [1 ]
Mangialasche, Francesca [1 ]
Johnell, Kristina [1 ,2 ]
Qiu, Chengxuan [1 ]
机构
[1] Stockholm Univ, Karolinska Inst, Aging Res Ctr, Dept Neurobiol Care Sci & Soc, S-10691 Stockholm, Sweden
[2] Stockholm Gerontol Res Ctr, Stockholm, Sweden
[3] Jining Med Univ, Sch Publ Hlth, Jining, Shandong, Peoples R China
[4] Karolinska Univ Hosp, Stockholm, Sweden
基金
瑞典研究理事会;
关键词
MANAGEMENT; DEMENTIA; DISEASE; BURDEN; ADULTS; HYPERTENSION; ASSOCIATION; GUIDELINES; MEN;
D O I
10.1371/journal.pone.0119582
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Background Cardiometabolic risk factors and related cardiovascular diseases represent major threats to healthy aging. Objective We aimed to estimate distribution, pharmacological treatment, and control of main cardiometabolic risk factors among older people. Methods This population-based study included 3363 participants (age >= 60 years, 64.9% women) in the Swedish National study on Aging and Care in Kungsholmen, in central Stockholm, Sweden (2001-2004). Data on demographics, cardiometabolic risk factors (hypertension, obesity, diabetes, and high cholesterol), and medication use were collected through face-to-face interviews, clinical examinations, laboratory tests, and the inpatient register. Cardiometabolic risk factors were defined following the most commonly used criteria. Prevalence was standardized using local census data. Results The age-and sex-standardized prevalence of diabetes, obesity, high cholesterol, and hypertension was 9.5%, 12.8%, 49.7%, and 74.9%, respectively. The prevalence of hypertension and diabetes increased with age, whereas the prevalence of obesity and high cholesterol decreased with age. Forty-nine percent of older adults had two or more cardiometabolic risk factors; 9.8% had three or more. Overall, 55.5% of people with hypertension, 50.3% with diabetes, and 25.0% with high cholesterol received pharmacological treatment. Of those treated pharmacologically, 49.4%, 38.1%, and 85.5% reached therapeutic goals for hypertension (blood pressure<150/90 mmHg), diabetes (glycated haemoglobin<7%), and high cholesterol (total cholesterol<6.22 mmol/l), respectively. Conclusions Hypertension, high cholesterol, and clustering of cardiometabolic risk factors were common among older people in Stockholm, but pharmacological treatment and control of these major factors can be improved. Appropriate management of cardiometabolic profiles among older people may help improve cardiovascular health and achieve healthy aging.
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页数:14
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