Diagnostic Comparison Of Troponin and Scube 1 Levels In Patients Diagnosed with Stemi and Nstemi In The Emergency Department

Objective: In the present study we aimed to compare the levels of troponin and SCUBE 1 markers to determine the diagnostic role of SCUBE 1 in patients with STEMI-NSTEMI. Methods: This study was prospectively conducted with 119 patients diagnosed with acute myocardial infarction at the emergency department of DiskapiYildirimBeyazit Training and Research Hospital and 30 control subjects between 01.10.2016 and 01.02.2017. The relationship between age, sex, acute myocardial infarction (AMI) type, white blood cell (WBC), lymphocyte, neutrophil, neutrophil/lymphocyte ratio, red cell distribution width (RDW), thrombocyte count, aspartate aminotransferase (AST), alanine aminotransferase (ALT), CK, CK-MB, troponin, and SCUBE 1 level was examined. Age, sex, and SCUBE 1 level were compared between the patient and control groups. Results: The patients had a mean age of 61.5 +/- 14.5 years, and 68.9% of them were male. The patients had a SCUBE 1 level of 79.7 ng/mL and the control group 53.2 ng/ml. SCUBE 1 level was comparable between the patients with acute myocardial infarction and the control group (p>0.05). A correlation was found between SCUBE 1 level and age (p>0.05).Women in the patient group had a significantly higher SCUBE 1 level (p<0.05). There was a positive correlation between the WBC, CKMB, and troponin levels, and SCUBE 1 level in the patient group.cor No correlation was found between SCUBE 1 level and neutrophil, lymphocyte, neutrophil/lymphocyte ratio, RDW, platelet, AST, ALT, and CK levels (p>0.05). There was no significant correlation between infarction type and SCUBE 1 level (p>0.05). Conclusions: SCUBE 1 level did not significantly rise in patients with acute myocardial infarction. As the test had lower sensitivity and specificity compared to the other markers, we believe that it is not suitable for practical use.