A qualitative study on the adverse reactions of mass treatment for lymphatic filariasis in Orissa, India

被引:5
作者
Babu, B., V [1 ,2 ]
机构
[1] Indian Council Med Res, New Delhi 110029, India
[2] Indian Council Med Res, Div Epidemiol, Reg Med Res Ctr, Bhubaneswar 751023, Orissa, India
关键词
Lymphatic filariasis; Mass drug administration; Adverse reactions; Qualitative study; Orissa; India; WUCHERERIA-BANCROFTI INFECTION; GLOBAL PROGRAM; DIETHYLCARBAMAZINE; IVERMECTIN; ALBENDAZOLE; COVERAGE; CHEMOTHERAPY; TRANSMISSION; STATE;
D O I
10.1016/S1995-7645(10)60033-8
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Objective: To describe the perceptions of community members and programme partners regarding severity, management and impact of adverse reactions on mass drug administration (MDA) compliance. Methods: Based on various qualitative data collected from five districts of Orissa, India, where MDA had been implemented during 2002 and 2004. The qualitative surveys included focus group discussions with community members and health workers, and semi structured interviews with key informants in the community, medical officers at primary health centres, district level health officers and private practitioners. Results: It showed that many people suffered from adverse reactions, though the reactions were not serious. The paper reported different ways of management of adverse reactions at the community level. The impact of adverse reactions on MDA compliance was serious, as many people did not consume the drug due to fear of adverse reactions. The rumours of adverse reactions and news in media deterred people from consuming the tablets. Conclusion: All categories of respondents indicates the need of more information to address the problem of adverse reactions during MDA. The present paper warrants incorporating the messages on adverse reactions during health communication and social mobilization campaigns of MDA.
引用
收藏
页码:55 / 58
页数:4
相关论文
共 24 条
[1]   Randomised placebo-controlled comparison of ivermectin and albendazole alone and in combination for Wuchereria bancrofti microfilaraemia in Haitian children [J].
Addiss, DG ;
Beach, MJ ;
Streit, TG ;
Lutwick, S ;
LeConte, FH ;
Lafontant, JG ;
Hightower, AW ;
Lammie, PJ .
LANCET, 1997, 350 (9076) :480-484
[2]   Coverage, compliance and some operational issues of mass drug administration during the programme to eliminate lymphatic filariasis in Orissa, India [J].
Babu, B ;
Kar, SK .
TROPICAL MEDICINE & INTERNATIONAL HEALTH, 2004, 9 (06) :702-709
[3]   Adverse reactions following mass drug administration during the Programme to Eliminate Lymphatic Filariasis in Orissa State, India [J].
Babu, BV ;
Rath, K ;
Kerketta, AS ;
Swain, BK ;
Mishra, S ;
Kar, SK .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 2006, 100 (05) :464-469
[4]   Factors responsible for coverage and compliance in mass drug administration during the programme to eliminate lymphatic filariasis in the East Godavari District, South India [J].
Babu, BV ;
Satyanarayana, K .
TROPICAL DOCTOR, 2003, 33 (02) :79-82
[5]  
BABU BV, 2004, ANN TROP MED PARASIT, V99, P101
[6]  
Biritwum RB, 1997, ANN TROP MED PARASIT, V91, P297, DOI 10.1080/00034989761148
[7]   Mass treatment to eliminate filariasis in Papua New Guinea [J].
Bockarie, MJ ;
Tisch, DJ ;
Kastens, W ;
Alexander, NDE ;
Dimber, Z ;
Bockarie, F ;
Ibam, E ;
Alpers, MP ;
Kazura, JW .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 347 (23) :1841-1848
[8]   Placebo-controlled community trial of four cycles of single-dose diethylcarbamazine or ivermectin against Wuchereria bancrofti infection and transmission in India [J].
Das, PK ;
Ramaiah, KD ;
Vanamail, P ;
Pani, SP ;
Yuvaraj, J ;
Balarajan, K ;
Bundy, DAP .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 2001, 95 (03) :336-341
[9]   TOLERANCE OF DIETHYLCARBAMAZINE BY MICROFILAREMIC AND AMICROFILARAEMIC INDIVIDUALS IN AN ENDEMIC AREA OF BANCROFTIAN FILARIASIS, RECIFE, BRAZIL [J].
DREYER, G ;
PIRES, ML ;
DEANDRADE, LD ;
LOPES, E ;
MEDEIROS, Z ;
TENORIO, J ;
COUTINHO, A ;
NOROES, J ;
FIGUEREDOSILVA, J .
TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1994, 88 (02) :232-236
[10]   The impact of 34 years of massive DEC chemotherapy on Wuchereria bancrofti infection and transmission:: the Maupiti cohort [J].
Esterre, P ;
Plichart, C ;
Sechan, Y ;
Nguyen, NL .
TROPICAL MEDICINE & INTERNATIONAL HEALTH, 2001, 6 (03) :190-195