Catalyst-free three-component reaction between 2-aminopyridines (or 2-aminothiazoles), aldehydes, and isocyanides in water

被引：118
作者：
Adib, Mehdi
Mahdavi, Mohammad
Noghani, Mahsa Alizadeh
Mirzaei, Peiman
机构：
[1] Univ Tehran, Univ Coll Sci, Sch Chem, Tehran, Iran
[2] Shahid Beheshti Univ, Dept Chem, Tehran, Iran
来源：
TETRAHEDRON LETTERS | 2007年 / 48卷 / 41期
关键词：
imidazo[1,2-a]pyridines; imidazo[2,1-b][1,3]thiazoles; isocyanides; three-component reactions; catalyst-free synthesis in water;
D O I：
10.1016/j.tetlet.2007.08.049
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A catalyst-free and convenient protocol is described for the preparation of 3-aminoimidazo[1,2-a]pyridines and 5-aminoimidazo[2,1-b][1,3]thiazoles via three-component reactions between 2-aminopyridines or 2-aminothiazoles, aldehydes, and isocyanides in water in good to excellent yields. (c) 2007 Elsevier Ltd. All rights reserved.
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收藏
页码：7263 / 7265
页数：3
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