Ptdins(3,5)P2 finds a partner

被引：5
|
作者：
Hicke, L [1 ]
机构：
[1] Northwestern Univ, Dept Biochem Mol Biol & Cell Biol, Evanston, IL 60208 USA
来源：
DEVELOPMENTAL CELL | 2003年 / 5卷 / 03期
关键词：
D O I：
10.1016/S1534-5807(03)00271-5
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Phosphatidylinositol-3,5-bisphosphate (PtdIns(3,5)P-2) is required for the sorting of a subset of membrane proteins at the late endosome. Unlike other phosphoinositides, binding partners for PtdIns(3,5)P-2 and its mechanism of action have not been characterized. New work by Friant et al. (2003) in this issue of Developmental Cell describes the identification of a yeast epsin-like protein that binds PtdIns(3,5)P-2 and functions in the transport of proteins through late endosomes to the lysosome-like vacuole.
引用
收藏
页码：363 / 364
页数：2
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