Manganese catalyzed switchable C-alkylation/alkenylation of fluorenes and indene with alcohols

被引：26

作者：

Mondal, Avijit ^{[1
]}

Sharma, Rahul ^{[1
]}

Pal, Debjyoti ^{[1
]}

Srimani, Dipankar ^{[1
]}

机构：

[1] Indian Inst Technol Guwahati, Dept Chem, Kamrup 781039, Assam, India

来源：

CHEMICAL COMMUNICATIONS | 2021年 / 57卷 / 80期

关键词：

BORROWING HYDROGEN; ALPHA-ALKYLATION; N-HETEROARENES; H ACTIVATION; KETONES; OLEFINATION; NITRILES;

D O I：

10.1039/d1cc03529k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The usage of earth-abundant, nontoxic transition metals in place of rare noble metals is a central goal in catalysis. This would be especially interesting when the reactivity and selectivity patterns can be tuned. Herein, we introduced the first Mn-catalyzed selective C-alkylation and olefination of fluorene, and indene with alcohols. Various substrates including benzylic, heteroaromatic, and aliphatic primary and secondary alcohols are employed as alkylating agents. Mechanistic investigations and a kinetic study underpin the involvement of the olefinated intermediate to furnish the alkylated product.

引用

页码：10363 / 10366

页数：4

共 52 条

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