ObjectiveTo examine the effects of direct oral anticoagulants (DOACs) on bleeding complications following dental surgeries. Subjects and MethodsThis 6-year retrospective study collected data from records of patients undergoing oral surgical procedures within a university setting. An electronic health record database was searched using current procedural terminology codes for oral surgical procedures. Information regarding patient, procedural factors, and postoperative complications were extracted. Data were analyzed by Fisher's exact test. ResultsOf patients who had a procedural code associated with oral surgery, only 0.11% (12/11,320) took a DOAC. Twelve patients (10 males, age ranging from 44 to 90years) underwent 17 surgeries by nine different practitioners involving 98 extractions, 14 alveoloplasties, two tuberosity reductions, and two tori removals. In nine cases, the DOAC was discontinued a mean of 52.5hrs prior to surgery (range 12-120hrs). Bleeding complications were not reported for patients whose drug was discontinued or continued. Documentation of drug continuation/discontinuation was poor. ConclusionsBleeding was not observed with direct oral anticoagulation use in this oral surgery cohort. Drug discontinuation/continuation was not a factor in bleeding outcomes, and direct oral anticoagulation interruption was variable and poorly documented.
机构:
Meir Hosp, Meir Med Ctr, Dept Ophthalmol, 59 Tchernichovsky St, IL-4428164 Kefar Sava, Israel
Tel Aviv Univ, Sackler Fac Med, Tel Aviv, IsraelMeir Hosp, Meir Med Ctr, Dept Ophthalmol, 59 Tchernichovsky St, IL-4428164 Kefar Sava, Israel
Maytal, Anat
Rosenblatt, Hadar Naidorf
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Kaplan Med Ctr, Dept Ophthalmol, Rehovot, IsraelMeir Hosp, Meir Med Ctr, Dept Ophthalmol, 59 Tchernichovsky St, IL-4428164 Kefar Sava, Israel
Rosenblatt, Hadar Naidorf
Rotem, Reut
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Shaare Zedek Med Ctr, Dept Obstet & Gynecol, Jerusalem, IsraelMeir Hosp, Meir Med Ctr, Dept Ophthalmol, 59 Tchernichovsky St, IL-4428164 Kefar Sava, Israel
Rotem, Reut
Segev, Fani
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机构:
Assuta Samson Med Ctr, Dept Ophthalmol, Ashdod, Israel
Ben Gurion Univ Negev, Joyce & Irwing Goldman Med Sch, Beer Sheva, IsraelMeir Hosp, Meir Med Ctr, Dept Ophthalmol, 59 Tchernichovsky St, IL-4428164 Kefar Sava, Israel
机构:
CHU Charleroi, Hop Andre Vesale, Serv Pharm, Montignies le Tilleul, BelgiumCHU Charleroi, Hop Andre Vesale, Serv Pharm, Montignies le Tilleul, Belgium
Peeterbroeck, Julie
Danguy, Christine
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CHU Charleroi, Hop Andre Vesale, Serv Pharm, Montignies le Tilleul, BelgiumCHU Charleroi, Hop Andre Vesale, Serv Pharm, Montignies le Tilleul, Belgium
Danguy, Christine
Lelubre, Christophe
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机构:
CHU Charleroi, Hop Andre Vesale, Expt Med Lab, Montignies le Tilleul, BelgiumCHU Charleroi, Hop Andre Vesale, Serv Pharm, Montignies le Tilleul, Belgium
Lelubre, Christophe
Meulemans, Martine
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机构:
CHU Charleroi, Hop Andre Vesale, Serv Geriatrie, Montignies le Tilleul, BelgiumCHU Charleroi, Hop Andre Vesale, Serv Pharm, Montignies le Tilleul, Belgium
Meulemans, Martine
Higuet, Sandra
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CHU Charleroi, Hop Andre Vesale, Serv Geriatrie, Montignies le Tilleul, BelgiumCHU Charleroi, Hop Andre Vesale, Serv Pharm, Montignies le Tilleul, Belgium
Higuet, Sandra
GERIATRIE ET PSYCHOLOGIE NEUROPSYCHIATRIE DE VIEILLISSEMENT,
2016,
14
(04):
: 406
-
412
机构:
Ochsner Hlth, Dept Pharm, 1514 Jefferson Highway, New Orleans, LA 70121 USAOchsner Hlth, Dept Pharm, 1514 Jefferson Highway, New Orleans, LA 70121 USA
Tijani, Aminat
Coons, Eric M.
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机构:
Ochsner Hlth, Dept Pharm, 1514 Jefferson Highway, New Orleans, LA 70121 USAOchsner Hlth, Dept Pharm, 1514 Jefferson Highway, New Orleans, LA 70121 USA
Coons, Eric M.
Mizuki, Britta
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机构:
Ochsner Hlth, Dept Pharm, 1514 Jefferson Highway, New Orleans, LA 70121 USAOchsner Hlth, Dept Pharm, 1514 Jefferson Highway, New Orleans, LA 70121 USA
Mizuki, Britta
Dermady, Miranda
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h-index: 0
机构:
Ochsner Hlth, Dept Pharm, 1514 Jefferson Highway, New Orleans, LA 70121 USAOchsner Hlth, Dept Pharm, 1514 Jefferson Highway, New Orleans, LA 70121 USA
Dermady, Miranda
Stanilova, Katerina
论文数: 0引用数: 0
h-index: 0
机构:
Ochsner Hlth, Dept Pharm, 1514 Jefferson Highway, New Orleans, LA 70121 USAOchsner Hlth, Dept Pharm, 1514 Jefferson Highway, New Orleans, LA 70121 USA
Stanilova, Katerina
Casey, Ashley L.
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机构:
Ochsner Hlth, Dept Pharm, 1514 Jefferson Highway, New Orleans, LA 70121 USAOchsner Hlth, Dept Pharm, 1514 Jefferson Highway, New Orleans, LA 70121 USA
Casey, Ashley L.
Alqudsi, Muhannad
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机构:
Ochsner Hlth, Dept Nephrol, New Orleans, LA USAOchsner Hlth, Dept Pharm, 1514 Jefferson Highway, New Orleans, LA 70121 USA
Alqudsi, Muhannad
Gastanaduy, Mariella
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h-index: 0
机构:
Ochsner Hlth, Ochsner Ctr Outcomes Res, New Orleans, LA USAOchsner Hlth, Dept Pharm, 1514 Jefferson Highway, New Orleans, LA 70121 USA
Gastanaduy, Mariella
Elmayan, Ardem
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h-index: 0
机构:
Ochsner Hlth, Ochsner Ctr Outcomes Res, New Orleans, LA USAOchsner Hlth, Dept Pharm, 1514 Jefferson Highway, New Orleans, LA 70121 USA
Elmayan, Ardem
Bamnolker, Adi
论文数: 0引用数: 0
h-index: 0
机构:
Ochsner Hlth, Dept Hosp Med, New Orleans, LA USAOchsner Hlth, Dept Pharm, 1514 Jefferson Highway, New Orleans, LA 70121 USA
Bamnolker, Adi
Velez, Juan Carlos Q.
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机构:
Ochsner Hlth, Dept Nephrol, New Orleans, LA USAOchsner Hlth, Dept Pharm, 1514 Jefferson Highway, New Orleans, LA 70121 USA
机构:
Houston Methodist Hosp, Dept Pharm, 6565 Fannin St,DB1-09, Houston, TX 77030 USA
Intermt Med Ctr, Dept Pharm, Salt Lake City, UT USAHouston Methodist Hosp, Dept Pharm, 6565 Fannin St,DB1-09, Houston, TX 77030 USA
机构:
Univ Paris 05, Fac Pharm, Inserm UMR S1140, 4 Ave Observ, F-75006 Paris, France
Hop Instruct Armees Percy, Serv Cardiol, 101 Ave Henri Barbusse, F-92140 Clamart, FranceFdn Adolphe Rothschild, Serv Anesthesie Reanimat, 25 Rue Manin, F-75019 Paris, France
Martin, Anne-Celine
Radu, Adrian
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机构:
Hop Foch, Serv Anesthesie, 40 Rue Worth, F-92150 Suresnes, FranceFdn Adolphe Rothschild, Serv Anesthesie Reanimat, 25 Rue Manin, F-75019 Paris, France
机构:
Hop Cochin, AP HP, Serv Anesthesie Reanimat, 27 Rue Faubourg St Jacques, F-75014 Paris, FranceFdn Adolphe Rothschild, Serv Anesthesie Reanimat, 25 Rue Manin, F-75019 Paris, France
Antona, Marion
Vasse, Marc
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h-index: 0
机构:
Hop Foch, Serv Biol Clin, 40 Rue Worth, F-92150 Suresnes, France
Univ Paris Sud, INSERM UMR S1176, 80 Rue Gen Leclerc, F-94276 Le Kremlin Bicetre, FranceFdn Adolphe Rothschild, Serv Anesthesie Reanimat, 25 Rue Manin, F-75019 Paris, France
Vasse, Marc
Golmard, Jean-Louis
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机构:
GH Pitie Salpetriere, AP HP, Dept Biostat, 47-83 Blvd Hop, F-75013 Paris, FranceFdn Adolphe Rothschild, Serv Anesthesie Reanimat, 25 Rue Manin, F-75019 Paris, France
机构:
Univ Paris 05, Fac Pharm, Inserm UMR S1140, 4 Ave Observ, F-75006 Paris, France
Hop Cochin, AP HP, Lab Hematol, 27 Rue Faubourg St Jacques, F-75014 Paris, France
Hop Pontchaillou, Lab Hematol, 2 Rue Henri le Guilloux, F-35000 Rennes, FranceFdn Adolphe Rothschild, Serv Anesthesie Reanimat, 25 Rue Manin, F-75019 Paris, France