Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours (NETs)

被引:441
作者
Ramage, John K. [1 ]
Ahmed, A. [2 ]
Ardill, J. [3 ]
Bax, N. [4 ]
Breen, D. J. [5 ]
Caplin, M. E. [6 ]
Corrie, P. [7 ]
Davar, J. [8 ]
Davies, A. H. [9 ]
Lewington, V. [10 ]
Meyer, T. [11 ]
Newell-Price, J. [12 ]
Poston, G. [13 ]
Reed, N. [14 ]
Rockall, A. [15 ]
Steward, W. [16 ]
Thakker, R. V. [17 ]
Toubanakis, C. [18 ]
Valle, J. [19 ]
Verbeke, C. [20 ]
Grossman, A. B. [17 ]
机构
[1] Basingstoke & N Hampshire Hosp, Basingstoke RG24 9NA, Hants, England
[2] Cty Durham & Darlington Fdn Trust, Dept Gastroenterol, Darlington, Durham, England
[3] Royal Victoria Hosp, Peptide Lab, Belfast BT12 6BA, Antrim, North Ireland
[4] Univ Sheffield, Dept Clin Pharmacol, Sheffield, S Yorkshire, England
[5] Southampton Gen Hosp, Dept Radiol, Southampton SO9 4XY, Hants, England
[6] UCL, Dept Gastroenterol, London, England
[7] Cambridge Univ Hosp NHS Fdn Trust, Addenbrookes Hosp, Dept Oncol, Cambridge, England
[8] Royal Free Hosp, Dept Cardiol, London NW3 2QG, England
[9] Univ Hosp Morecambe Bay Fdn Trust, Dept Gastroenterol, Barrow In Furness, Cumbria, England
[10] Kings Coll London, London WC2R 2LS, England
[11] UCL, Dept Oncol, London, England
[12] Univ Sheffield, Dept Endocrinol, Sheffield, S Yorkshire, England
[13] Univ Liverpool, Dept Surg, Liverpool L69 3BX, Merseyside, England
[14] Beatson Ctr, Dept Oncol, Glasgow, Lanark, Scotland
[15] Queen Marys Univ, Dept Radiol, London, England
[16] Univ Leicester, Dept Oncol, Leicester, Leics, England
[17] Univ Oxford, Acad Dept Endocrinol Diabet & Metab, Oxford, England
[18] Royal Free Hosp, Dept Gastroenterol, London NW3 2QG, England
[19] Christie Hosp NHS Fdn Trust, Dept Med Oncol, Manchester, Lancs, England
[20] St James Univ Hosp, Dept Histopathol, Leeds, W Yorkshire, England
基金
英国惠康基金;
关键词
SOMATOSTATIN-RECEPTOR SCINTIGRAPHY; QUALITY-OF-LIFE; PANCREATIC ENDOCRINE TUMORS; LAPAROSCOPIC RADIOFREQUENCY ABLATION; BRAIN NATRIURETIC PEPTIDE; LONG-TERM SURVIVAL; ISLET-CELL TUMORS; HEPATIC ARTERIAL CHEMOEMBOLIZATION; STREPTOZOCIN PLUS FLUOROURACIL; ENETS CONSENSUS GUIDELINES;
D O I
10.1136/gutjnl-2011-300831
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
These guidelines update previous guidance published in 2005. They have been revised by a group who are members of the UK and Ireland Neuroendocrine Tumour Society with endorsement from the clinical committees of the British Society of Gastroenterology, the Society for Endocrinology, the Association of Surgeons of Great Britain and Ireland (and its Surgical Specialty Associations), the British Society of Gastrointestinal and Abdominal Radiology and others. The authorship represents leaders of the various groups in the UK and Ireland Neuroendocrine Tumour Society, but a large amount of work has been carried out by other specialists, many of whom attended a guidelines conference in May 2009. We have attempted to represent this work in the acknowledgements section. Over the past few years, there have been advances in the management of neuroendocrine tumours, which have included clearer characterisation, more specific and therapeutically relevant diagnosis, and improved treatments. However, there remain few randomised trials in the field and the disease is uncommon, hence all evidence must be considered weak in comparison with other more common cancers.
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收藏
页码:6 / 32
页数:27
相关论文
共 411 条
[91]   Temozolomide as monotherapy is effective in treatment of advanced malignant neuroendocrine tumors [J].
Ekeblad, Sara ;
Sundin, Anders ;
Janson, Eva Tiensuu ;
Welin, Staffan ;
Granberg, Dan ;
Kindmark, Henrik ;
Dunder, Kristina ;
Kozlovacki, Gordana ;
Orlefors, Hakan ;
Sigurd, Mattias ;
Oberg, Kjell ;
Eriksson, Barbro ;
Skogseid, Britt .
CLINICAL CANCER RESEARCH, 2007, 13 (10) :2986-2991
[92]   Prognostic Factors and Survival in 324 Patients with Pancreatic Endocrine Tumor Treated at a Single Institution [J].
Ekeblad, Sara ;
Skogseid, Britt ;
Dunder, Kristina ;
Oberg, Kjell ;
Eriksson, Barbro .
CLINICAL CANCER RESEARCH, 2008, 14 (23) :7798-7803
[93]   Liver resection (and associated extrahepatic resections) for metastatic well-differentiated endocrine tumors: A 15-year single center prospective study [J].
Elias, D ;
Lasser, P ;
Ducreux, M ;
Duvillard, P ;
Ouellet, JF ;
Dromain, C ;
Schlumberger, M ;
Pocard, M ;
Boige, V ;
Miquel, C ;
Baudin, E .
SURGERY, 2003, 133 (04) :375-382
[94]   STREPTOZOCIN PLUS FLUOROURACIL VERSUS DOXORUBICIN THERAPY FOR METASTATIC CARCINOID-TUMOR [J].
ENGSTROM, PF ;
LAVIN, PT ;
MOERTEL, CG ;
FOLSCH, E ;
DOUGLASS, HO .
JOURNAL OF CLINICAL ONCOLOGY, 1984, 2 (11) :1255-1259
[95]   Tumor markers in neuroendocrine tumors [J].
Eriksson, B ;
Öberg, K ;
Stridsberg, M .
DIGESTION, 2000, 62 :33-38
[96]   Consensus guidelines for the management of patients with digestive neuroendocrine tumors -: Well-differentiated jejunal-ileal tumor/carcinoma [J].
Eriksson, Barbro ;
Kloeppel, Guenter ;
Krenning, Eric ;
Ahlman, Hakan ;
Ploeckinger, Ursula ;
Wiedenmann, Bertram ;
Arnold, Rudolf ;
Auernhammer, Christoph ;
Koerner, Meike ;
Rindi, Guido ;
Wildi, Stefan .
NEUROENDOCRINOLOGY, 2008, 87 (01) :8-19
[97]  
Eriksson BK, 1998, CANCER, V83, P2293, DOI 10.1002/(SICI)1097-0142(19981201)83:11<2293::AID-CNCR8>3.0.CO
[98]  
2-E
[99]   Surgery and radiofrequency ablation for treatment of liver metastases from midgut and foregut carcinoids and endocrine pancreatic tumors [J].
Eriksson, John ;
Stalberg, Peter ;
Nilsson, Anders ;
Krause, Johan ;
Lundberg, Christina ;
Skogseid, Britt ;
Granberg, Dan ;
Eriksson, Barbro ;
Akerstom, Goran ;
Hellman, Per .
WORLD JOURNAL OF SURGERY, 2008, 32 (05) :930-938
[100]  
FAHRENKAMP AG, 1995, VIRCHOWS ARCH, V426, P361