Correction of copper deficiency improves erythropoietin unresponsiveness in hemodialysis patients with anemia

被引：27

作者：

Higuchi, Terumi ^{[1
]}

Matsukawa, Yoshihiro ^{[2
]}

Okada, Kazuyoshi ^{[1
]}

Oikawa, Osamu ^{[1
]}

Yamazaki, Toshio ^{[1
]}

Ohnishi, Yoshihiko ^{[1
]}

Fujita, Takayuki ^{[1
]}

Fukuda, Noboru ^{[1
]}

Soma, Masayoshi ^{[1
]}

Matsumoto, Koichi ^{[1
]}

机构：

[1] Nihon Univ, Sch Med, Dept Med, Div Nephrol & Endocrinol,Itabashi Ku, Tokyo 1738610, Japan

[2] Nihon Univ, Sch Med, Dept Med, Div Hematol & Rheumatol, Tokyo 1738610, Japan

来源：

INTERNAL MEDICINE | 2006年 / 45卷 / 05期

关键词：

copper deficiency; anemia; enteral nutrition; erythropoietin;

D O I：

10.2169/internalmedicine.45.1541

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We have encountered five hemodialysis patients who had received enteral nutrition and recovered from erythropoietin- resistant anemia with neutropenia after the correction of copper deficiency. We reduced the required doses of recombinant human erythropoietin (rHuEPO) to maintain the target hematocrit levels and three patients were finally weaned from the rHuEPO therapy. Thus, copper deficiency is involved in erythropoietin-resistant anemia in hemodialysis patients.

引用

页码：271 / 273

页数：3

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