FACILE ACCESS TO 3-ALKYL-SUBSTITUTED 3-HYDROPEROXY-2,4-PYRROLIDINEDIONES USING MANGANESE(III)-CATALYZED AEROBIC OXIDATION

被引：13

作者：

Haque, M. Aminul ^{[1
]}

Nishino, Hiroshi ^{[1
]}

机构：

[1] Kumamoto Univ, Dept Chem, Grad Sch Sci & Technol, Kumamoto 8608555, Japan

来源：

SYNTHETIC COMMUNICATIONS | 2012年 / 42卷 / 04期

基金：

日本学术振兴会;

关键词：

Aerobic oxidation; catalytic oxidation; hydroperoxidation; hydroperoxypyrrolidinediones; manganese(III) acetate; 2,4-pyrrolidinediones; DERIVATIVES; ARTEMISININ; PHENYLBUTAZONE; PEROXIDES;

D O I：

10.1080/00397911.2010.528129

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

3-Alkyl-substituted 2,4-pyrrolidinediones were directly oxidized under very mild manganese(III)-catalyzed aerobic oxidation conditions to give the corresponding 3-hydroperoxy-2,4-pyrrolidinediones in quantitative yields. The scope and limitations for the synthesis of the hydroperoxyprrolidinediones are described.

引用

页码：608 / 619

页数：12

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