A new protocol for Biginelli (or like) reaction under solvent-free grinding method using Fe (NO3)3•9H2O as catalyst

被引：35

作者：

Phukan, Mridula ^{[1
]}

Kalita, Monoj Kumar ^{[1
]}

Borah, Ruli ^{[1
]}

机构：

[1] A Cent Univ, Dept Chem Sci, Tezpur Univ, Tezpur 784028, Assam, India

来源：

GREEN CHEMISTRY LETTERS AND REVIEWS | 2010年 / 3卷 / 04期

关键词：

dihydropyrimidinone; multicomponent; solid state; clayfen; ONE-POT SYNTHESIS; 3-COMPONENT CYCLOCONDENSATION REACTION; EFFICIENT SYNTHESIS; 3,4-DIHYDROPYRIMIDIN-2(1H)-ONES; CONDENSATION; ACID; DIHYDROPYRIMIDINONES; IMIDAZOLE; BLOCKERS;

D O I：

10.1080/17518253.2010.487841

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new protocol for Biginelli (or like) reaction has been developed under solvent-free grinding method using catalytic amount of hydrated ferric nitrate or clayfen. The advantage of this novel protocol lies in the avoidance of organic solvent, high yield, energy efficiency, variation of substrates, and use of inexpensive catalyst. The recycling of catalyst is also possible with clayfen for more than three times. Furthermore, the catalytic activity of ferric nitrate retains its efficiency in methanol and acetone as reaction medium. [GRAPHICS] .

引用

页码：329 / 334

页数：6

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