Objective: This study uses a modelling approach to compare the potential impact of future risk factor scenarios relating to smoking, physical activity levels, dietary salt, saturated fat intake, mean body mass index (BMI) levels, diabetes prevalence and fruit and vegetable (F&V) consumption on future coronary heart disease (CHD) mortality in Turkey for year 2025. Design: A CHD mortality model previously developed and validated in Turkey was extended to predict potential trends in CHD mortality from 2008 to 2025. Setting: Using risk factor trends data from recent surveys as a baseline, we modelled alternative evidence-based future risk factor scenarios (modest/ideal scenarios). Probabilistic sensitivity analyses were conducted to account for uncertainties. Subject: Projected populations in 2025 (aged 25-84) of 54 million in Turkey. Results: Assuming lower mortality, modest policy changes in risk factors would result in similar to 25 635 (range: 20 290-31 125) fewer CHD deaths in the year 2025; 35.6% attributed to reductions in salt consumption, 20.9% to falls in diabetes, 14.6% to declines in saturated fat intake and 13.6% to increase in F&V intake. In the ideal scenario, 45 950 (range: 36 780-55 450) CHD deaths could be prevented in 2025. Again, 33.2% of this would be attributed to reductions in salt reduction, 19.8% to increases in F&V intake, 16.7% to reductions in saturated fat intake and 14.0% to the fall in diabetes prevalence. Conclusions: Only modest risk factor changes in salt, saturated/unsaturated fats and F&V intake could prevent around 16 000 CHD deaths in the year 2025 in Turkey, even assuming mortality continues to decline. Implementation of population-based, multisectoral interventions to reduce salt and saturated fat consumption and increase F&V consumption should be scaled up in Turkey.
机构:
Hop Paul Brousse, INSERM, Ctr Res Epidemiol & Populat Hlth, U1018, F-94807 Villejuif, France
Univ Versailles, UMRS 1018, Versailles, FranceHop Paul Brousse, INSERM, Ctr Res Epidemiol & Populat Hlth, U1018, F-94807 Villejuif, France
Nabi, Hermann
Shipley, Martin J.
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UCL, Dept Epidemiol & Publ Hlth, London WC1E 6BT, EnglandHop Paul Brousse, INSERM, Ctr Res Epidemiol & Populat Hlth, U1018, F-94807 Villejuif, France
Shipley, Martin J.
Vahtera, Jussi
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Univ Turku, Dept Publ Hlth, SF-20500 Turku, Finland
Turku Univ Hosp, Turku, Finland
Finnish Inst Occupat Hlth, Helsinki, FinlandHop Paul Brousse, INSERM, Ctr Res Epidemiol & Populat Hlth, U1018, F-94807 Villejuif, France
Vahtera, Jussi
Hall, Martica
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Univ Pittsburgh, Sch Med, Dept Psychiat, Pittsburgh, PA 15260 USAHop Paul Brousse, INSERM, Ctr Res Epidemiol & Populat Hlth, U1018, F-94807 Villejuif, France
Hall, Martica
Korkeila, Jyrki
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Univ Turku, Dept Psychiat, SF-20500 Turku, Finland
Harjavalta Hosp, Harjavalta, FinlandHop Paul Brousse, INSERM, Ctr Res Epidemiol & Populat Hlth, U1018, F-94807 Villejuif, France
Korkeila, Jyrki
Marmot, Michael G.
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UCL, Dept Epidemiol & Publ Hlth, London WC1E 6BT, EnglandHop Paul Brousse, INSERM, Ctr Res Epidemiol & Populat Hlth, U1018, F-94807 Villejuif, France
Marmot, Michael G.
Kivimaki, Mika
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机构:
UCL, Dept Epidemiol & Publ Hlth, London WC1E 6BT, England
Finnish Inst Occupat Hlth, Helsinki, FinlandHop Paul Brousse, INSERM, Ctr Res Epidemiol & Populat Hlth, U1018, F-94807 Villejuif, France
Kivimaki, Mika
Singh-Manoux, Archana
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Univ Versailles, UMRS 1018, Versailles, France
UCL, Dept Epidemiol & Publ Hlth, London WC1E 6BT, England
Hop Ste Perine, AP HP, Ctr Gerontol, Paris, FranceHop Paul Brousse, INSERM, Ctr Res Epidemiol & Populat Hlth, U1018, F-94807 Villejuif, France