Hot-injection synthesis of iron/iron oxide core/shell nanoparticles for T2 contrast enhancement in magnetic resonance imaging

被引：58

作者：

Herman, David A. J. ^{[1
,2
]}

Ferguson, Peter ^{[3
]}

Cheong, Soshan ^{[1
,2
,4
]}

Hermans, Ian F. ^{[3
]}

Ruck, Ben J. ^{[1
,2
]}

Allan, Kathryn M. ^{[1
,2
]}

Prabakar, Sujay ^{[1
,2
]}

Spencer, John L. ^{[1
,2
]}

Lendrum, Conrad D. ^{[4
]}

Tilley, Richard. D. ^{[1
,2
]}

机构：

[1] Victoria Univ Wellington, Sch Chem & Phys Sci, Wellington, New Zealand

[2] Victoria Univ Wellington, MacDiarmid Inst Adv Mat & Nanotechnol, Wellington, New Zealand

[3] Malaghan Inst Med Res, Wellington, New Zealand

[4] Ind Res Ltd, Lower Hutt, New Zealand

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 32期

关键词：

IRON NANOPARTICLES; FUNCTIONALIZATION; STABILIZATION; OXIDATION;

D O I：

10.1039/c1cc13416g

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Here we report a new, bench-top synthesis for iron/iron oxide core/shell nanoparticles via the thermal decomposition of Fe(eta(5)-C6H3Me4)(2). The iron/iron oxide core/shell nanoparticles are superparamagnetic at room temperature and show improved negative contrast in T-2-weighted MR imaging compared to pure iron oxides nanoparticles, and have a transverse relaxivity (r(2)) of 332 mM(-1) s(-1).

引用

页码：9221 / 9223

页数：3

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