Acute Fibrinous and Organizing Pneumonia with Myelodysplastic Syndrome: Corticosteroid Monotherapy Led to Successful Ventilator Weaning

被引：9

作者：

Yamamoto, Mari ^{[1
]}

Murata, Kengo ^{[1
]}

Kiriu, Takahiro ^{[1
]}

Kouzai, Yasuji ^{[1
]}

Takamori, Mikio ^{[1
]}

机构：

[1] Tokyo Metropolitan Tama Med Ctr, Fuchu, Tokyo, Japan

来源：

INTERNAL MEDICINE | 2016年 / 55卷 / 21期

关键词：

acute fibrinous and organizing pneumonia; myelodysplastic syndromes; mechanical ventilation; corticosteroid monotherapy;

D O I：

10.2169/internalmedicine.55.6864

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 62-year-old man with myelodysplastic syndrome (MDS) presented to our hospital with a high fever. Although treatment with broad-spectrum antibiotics was initiated, his respiratory status worsened to the point that he required mechanical ventilation. However, he was successfully treated with a corticosteroid without immunosuppression. Sequential transbronchial lung biopsies revealed abundant fibrin exudate in the alveolar spaces, which was subsequently replaced by fibroblasts, showing that acute fibrinous and organizing pneumonia (AFOP) gradually changes into organizing pneumonia. Our case demonstrated both the efficacy of corticosteroid-monotherapy and the histological course of AFOP.

引用

页码：3155 / 3159

页数：5

共 15 条

[1]

Beasley MB, 2002, ARCH PATHOL LAB MED, V126, P1064

[2] Severe acute fibrinous and organizing pneumonia (AFOP) causing ventilatory failure: Successful treatment with mycophenolate mofetil and corticosteroids [J].

Bhatti, Sabha ;

Hakeem, Abdul ;

Torrealba, Jose ;

McMahon, Joseph P. ;

Meyer, Keith C. .

RESPIRATORY MEDICINE, 2009, 103 (11) :1764-1767

[3]

Feng AN, 2014, INT J CLIN EXP PATHO, V7, P4493

[4]

HORIIKE S, 1990, CANCER-AM CANCER SOC, V65, P1350, DOI 10.1002/1097-0142(19900315)65:6<1350::AID-CNCR2820650617>3.0.CO

[5]

2-J

[6] Severe Acute Fibrinous and Organizing Pneumonia with Acute Respiratory Distress Syndrome [J].

Kang, Hyo Jae ;

Choi, Sun Mi ;

Jeong, Yun Jeong ;

Park, Jong Sun ;

Lee, Sei Won ;

Yoon, Ho Il ;

Lee, Jae Ho ;

Lee, Choon-Tack ;

Cho, Young-Jae .

TUBERCULOSIS AND RESPIRATORY DISEASES, 2011, 71 (05) :368-372

[7]

Komiya I, 1991, CANCER, V1, P67

[8] Severe Acute Respiratory Failure Secondary to Acute Fibrinous and Organizing Pneumonia Requiring Mechanical Ventilation: A Case Report and Literature Review [J].

Lopez-Cuenca, Sonia ;

Morales-Garcia, Silvia ;

Martin-Hita, Ana ;

Frutos-Vivar, Fernando ;

Fernandez-Segoviano, Pilar ;

Esteban, Andres .

RESPIRATORY CARE, 2012, 57 (08) :1337-1341

[9] STEROID-RESPONSIVE PULMONARY DISORDERS ASSOCIATED WITH MYELODYSPLASTIC SYNDROMES WITH DER(1Q-7P) CHROMOSOMAL ABNORMALITY [J].

MATSUSHIMA, T ;

MURAKAMI, H ;

KIM, K ;

UCHIUMI, H ;

MURATA, N ;

TAMURA, J ;

SAWAMURA, M ;

KARASAWA, M ;

NARUSE, T ;

TSUCHIYA, J .

AMERICAN JOURNAL OF HEMATOLOGY, 1995, 50 (02) :110-115

[10] Myelodysplastic Syndrome and Autoimmunity: A Case Report of an Unusual Presentation of Myelodysplastic Syndrome [J].

Merrill, Andrea L. ;

Smith, Hedy .

CASE REPORTS IN HEMATOLOGY, 2011, 2011

← 1 2 →