ADHD in adolescents with borderline personality disorder

被引:49
作者
Speranza, Mario [1 ,2 ,3 ]
Revah-Levy, Anne [2 ,3 ,4 ]
Cortese, Samuele [5 ]
Falissard, Bruno [2 ,3 ]
Pham-Scottez, Alexandra [2 ,3 ,6 ]
Corcos, Maurice [2 ,3 ,7 ]
机构
[1] Ctr Hosp Versailles, Serv Pedopsychiat, Le Chesnay, France
[2] Univ Paris Sud, INSERM U669, Paris, France
[3] Univ Paris 05, UMR S0669, Paris, France
[4] Hop Argenteuil, Ctr Soins Psychotherapeut Transit Adolescents, F-95107 Argenteuil, France
[5] NYU, Ctr Child Study, Inst Pediat Neurosci, New York, NY 10016 USA
[6] Hop St Anne, Clin Malad Mentales & Encephale, F-75674 Paris, France
[7] Inst Mutualiste Montsouris, Dept Psychiat Adolescent & Jeune Adulte, Paris, France
来源
BMC PSYCHIATRY | 2011年 / 11卷
关键词
ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; DEFICIT HYPERACTIVITY DISORDER; BARRATT IMPULSIVENESS SCALE; K-SADS-PL; PSYCHIATRIC-DISORDERS; ORBITOFRONTAL CORTEX; RESPONSE-INHIBITION; CONDUCT PROBLEMS; FOLLOW-UP; SCHIZOPHRENIA;
D O I
10.1186/1471-244X-11-158
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Background: The aims of this study were to assess the prevalence of a comorbid Attention Deficit Hyperactivity Disorder (ADHD) diagnosis in Borderline Personality Disorder (BPD), and its impact on the clinical presentation of BPD in adolescents, and to determine which type of impulsivity specifically characterizes adolescents with BPD-ADHD. Methods: ADHD diagnoses were sought in a sample of 85 DSM-IV BPD adolescents drawn from the EURNET BPD. Axis-I and -II disorders were determined with the K-SADS-PL and the SIDP-IV, respectively. Impulsivity was assessed with the BIS-11. Results: 11% (N = 9) of BPD participants had a current ADHD diagnosis. BPD-ADHD adolescents showed higher prevalence of Disruptive disorders (Chi(2) = 9.09, p = 0.01) and a non-significant trend for a higher prevalence of other cluster B personality disorders (Chi(2) = 2.70, p = 0.08). Regression analyses revealed a significant association between Attentional/Cognitive impulsivity scores and ADHD (Wald Z = 6.69; p = 0.01; Exp(B) = 2.02, CI 95% 1.19-3.45). Conclusions: Comorbid ADHD influences the clinical presentation of adolescents with BPD and is associated with higher rates of disruptive disorders, with a trend towards a greater likelihood of cluster B personality disorders and with higher levels of impulsivity, especially of the attentional/cognitive type. A subgroup of BPD patients may exhibit developmentally driven impairments of the inhibitory system persisting since childhood. Specific interventions should be recommended for this subsample of BPD adolescents.
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页数:9
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