Evidence-Based Treatments in Pemphigus Vulgaris and Pemphigus Foliaceus

被引:16
作者
Frew, John W. [2 ]
Martin, Linda K. [3 ]
Murrell, Dedee F. [1 ]
机构
[1] Univ New S Wales, St George Hosp, Dept Dermatol, Sydney, NSW 2217, Australia
[2] Univ Sydney, Fac Med, Sydney, NSW 2006, Australia
[3] St Thomas Hosp, St Johns Inst Dermatol, London SE1 7EH, England
关键词
Pemphigus; Evidence-based medicine; Immunosuppressive therapy; Immunomodulating therapy; DOUBLE-BLIND; MYCOPHENOLATE-MOFETIL; ORAL PREDNISOLONE; TRIAL; MULTICENTER; MANAGEMENT; REGIMENS; ADJUVANT; THERAPY; LESIONS;
D O I
10.1016/j.det.2011.07.001
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Treatment modalities in pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are many and varied, although level 1 evidence supporting their use is limited. To date, only 2 systematic reviews exist to support the use of different treatment modalities to control this group of conditions. Overall, within the literature, the quality of trials comparing treatment modalities is poor. Cohort sizes are small, methodologies are varied, and standardized outcome measurements are lacking. The authors aim to present a comprehensive view of the level 1 evidence that exists for common treatment modalities used in PV and PF.
引用
收藏
页码:599 / +
页数:9
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