Probing the Structural and Antimicrobial Study on a Sol-Gel Derived Velosef-Loaded Bioactive Calcium Magneso-Silicate Xerogel

被引：17
作者：
Abouelnaga, Amal M. [1 ]
Meaz, Talaat M. [1 ]
Othman, Abdelmageed M. [2 ]
Ghazy, Riyad A. [1 ]
El Nahrawy, Amany M. [3 ]
机构：
[1] Tanta Univ, Fac Sci, Phys Dept, Tanta 31527, Egypt
[2] Natl Res Ctr, Microbial Chem Dept, Genet Engn & Biotechnol Res Div, 33 El Bohouth St, Cairo 12622, Egypt
[3] Natl Res Ctr, Phys Res Div, Solid State Phys Dept, 33 El Bohouth St, Cairo 12622, Egypt
来源：
SILICON | 2021年 / 13卷 / 03期
关键词：
Sol-gel calcium magneso-silicate; SiO2; Xerogel; UV-Vis absorbance; Antimicrobial activity; HYBRID HYDROGEL; SODIUM-SILICATE; IR; NANOPARTICLES; REMOVAL; GLASSES;
D O I：
10.1007/s12633-020-00448-8
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
The nature of the opening silicate- based surface affects the chemical interaction, spectroscopic and antimicrobial efficiency. The aim of this approach was to evaluate the spectroscopic properties and the antimicrobial activity of Velosef-loaded bioactive calcium magneso-silicate xerogel (CMS) prepared by green sol gel method. Loading of Velosef drug into the controlled calcium magneso-silicate xerogel was analyzed by XRD, HR-TEM, FE-SEM, and UV-Vis-absorption spectra. The particle distribution and surface morphological analysis indicated the establishment of calcium magneso-silicate/Velosef xero-gels. The UV-absorption exposed an increase in the refractive index and the band gap values of the xerogels with increasing Velosef content. The prepared calcium magneso-silicate/Volesef loaded xerogel samples exerted higher antimicrobial activity versus the three tested model microorganisms. The highest antimicrobial efficiency was recorded in case of Candida albicans at concentration of 0.03 wt% from Volesef loaded nanocomposites (37 mm), whereas the lower antimicrobial efficiency (26 mm) was recorded versus B. mycoides at the same concentration. These results appears that the calcium magneso-silicate xerogel-based to be a promising nano-structures material for spectroscopic and bio-applications.
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收藏
页码：623 / 631
页数：9
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